Results 111 to 120 of about 16,166,284 (299)

Allocation of Resources for Basic Research in a Mission Oriented Governmental Agency

open access: yes
Operations Research ...
Brown, Melvin (Creatorcre)   +4 more
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The need for controls in case control studies

open access: yesNorth American Journal of Medical Sciences, 2014
Dear Editor, This is regarding the article entitled “Relationship between type 2 diabetic retinopathy and periodontal disease in Iranian Adults” published in North American Journal of Medical Sciences 2014; 6:139-44.[1] As per the authors, the study was designed to evaluate the frequency of periodontal disease in patients with type 2 diabetes ...
openaire   +3 more sources

Analysis of Congestion Problems in UCDF Operations

open access: yes
Operations Research ...
Hartman, James K. (Creatorcre)
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Application of Pert in Plant Construction Scheduling in the Ohio Brass Company

open access: yes
Operations Research ...
Mathis, Samuel J., Jr. (Creatorcre)   +2 more
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Applications of binary programming to R&D project selection problems

open access: yes
Operations Research ...
Rao, A. K. (Creatorcre)
core  

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Determinants of induced abortion among second-trimester pregnant women attending Dessie City health facilities, Northeast Ethiopia: a case-control study

open access: yesHIV & AIDS Review. International Journal of HIV-Related Problems
Introduction Globally, 10-15% of induced abortions occur in the second-trimester period, over half of which is considered unsafe, and disproportionately contribute to maternal deaths.
Elsabeth Addisu   +4 more
doaj   +1 more source

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