Results 241 to 250 of about 22,838,112 (390)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Autonomic and baroreflex regulations in syndromic and non-syndromic aortopathies: a case-control study. [PDF]

Front Physiol
Cairo B, Udugampolage NS, Gelpi F, Bari V, Salvi P, Angolani M, Taurino J, Porta A, Pini A.   +8 more
europepmc   +1 more source

Enteral feeding as sole treatment for Crohn's disease: controlled trial of whole protein v amino acid based feed and a case study of dietary challenge. [PDF]

, 1991
A.H. Raouf, V Hildrey, J. Daniel, R J Walker, N Krasner, Erik Elias, J. Rhodes   +6 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Elabela as a predictive biomarker for placenta accreta spectrum: a case-control study. [PDF]

BMC Pregnancy Childbirth
Akbulut ÖV, Sümer D, Ağaoğlu RT, Kurt A, Kından A, Filiz AA, Üçok BS, Çağlar AT, Yücel KY.   +8 more
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Patient Portal Access and Missed Medical Appointments: A Case-Control Study. [PDF]

J Patient Exp
Goldstein S, Buuck K, Thompson H, Yu R, Small N, des Bordes J, Rianon N.   +6 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Altered Plasma Endocannabinoids and Oxylipins in Adolescents with Major Depressive Disorders: A Case-Control Study. [PDF]

Nutrients
Chakravarty A, Sreetharan A, Osuna E, Herter-Aeberli I, Häberling I, Baumgartner J, Berger GE, Hersberger M.   +7 more
europepmc   +1 more source

Referee report. For: A pilot study to explore utility of electronic informed consent in a low- income setting; the case of a Controlled human infection study in Blantyre, Malawi [version 2; peer review: 4 approved with reservations]

Erisa Mwaka
openalex   +1 more source