Results 21 to 30 of about 3,026,493 (306)
Bias in case‐crossover studies of medications due to persistent use: A simulation study [PDF]
AbstractPurposeThe case‐crossover design is increasingly used to evaluate the effects of chronic medications; however, as traditionally implemented in pharmacoepidemiology, with referent period preceding the outcome, it may lead to bias in the presence of persistent exposures.
Katsiaryna Bykov +5 more
openaire +2 more sources
Background: The acute effects of exposure to ambient particulate matter with an aerodynamic diameter ≤1 μm (PM1) on cardiovascular disease (CVD) mortality remain unclear.
Ruijun Xu +9 more
doaj +1 more source
Case-crossover studies of occupational trauma: methodological caveats [PDF]
Objectives—The case-crossover study design was developed to examine triggers for the onset of myocardial infarction. This paper seeks to examine selected methodological issues when applying the case-crossover method to the study of traumatic injuries in the work environment.Methods—Researchers known to be working on occupational case-crossover studies ...
G S, Sorock +4 more
openaire +2 more sources
Background: Epidemiology studies have shown a consistently increased risk of acute myocardial infarction (AMI) correlated with particulate matter (PM) exposure. However, little is known about the association with specific AMI subtypes. In this work, we
Qian Zhang
doaj +1 more source
Background Surgery is a major transient risk factor for venous thromboembolism (VTE). However, the impact of major surgery as a VTE trigger has been scarcely investigated using a case-crossover design.
Dana Meknas +3 more
doaj +1 more source
Sample size estimation for case‐crossover studies
Case‐crossover study designs are observational studies used to assess postmarket safety of medical products (eg, vaccines or drugs). As a case‐crossover study is self‐controlled, its advantages include better control for confounding because the design controls for any time‐invariant measured and unmeasured confounding and potentially greater ...
Sai Dharmarajan +2 more
openaire +4 more sources
Background and Objective: It has been suggested to avoid cilostazol, the first-line therapy for peripheral arterial disease, in patients with congestive heart failure (HF). The objective of this study was to evaluate the risk of hospitalization for heart
Cho-Kai Wu +7 more
doaj +1 more source
Triggers for Preeclampsia Onset: a Case‐Crossover Study
AbstractBackgroundRisk factors for preeclampsia are well established, whereas, the triggers associated with timing of preeclampsia onset are not. The aim of this study was to establish whether recent infection or other triggers were associated with timing of preeclampsia onset.MethodsWe used a case‐crossover design with preeclampsia cases serving as ...
Jane B, Ford +5 more
openaire +3 more sources
Background: Children’s respiratory health demonstrates particular sensitivity to air pollution. Existing evidence investigating the association between short-term ozone (O3) exposure and childhood pneumonia remains insufficient and inconsistent ...
Huan Wang +7 more
doaj +1 more source
Acute triggers of myocardial infarction: A case-crossover study
Acute myocardial infarction (AMI) is one of the most preventable non-communicable diseases in human. Identifying triggers of myocardial infarction (MI) and prevention ways of exposure-induced complications can reduce morbidity and mortality in people at risk.The aim of this study was to identify the emotional, environmental, physical and chemical ...
Maryam Ghiasmand +3 more
openaire +3 more sources

