Impact of extreme temperature on congenital heart disease mortality: a population-based nationwide case-crossover study. [PDF]
He Q +12 more
europepmc +1 more source
Advanced Experiment Design Strategies for Drug Development
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang +3 more
wiley +1 more source
Characterizing pediatric discharge diagnoses associated with daily extreme heat exposure in the Midwestern US: A retrospective case-crossover study. [PDF]
Oerther S +5 more
europepmc +1 more source
In this work, the Doubao large language model (LLM) is involved in the formula derivation processes for Hubbard U determination regarding the second‐order perturbations of the chemical potential. The core ML tool is optimized for physical domain knowledge, which is not limited to parameter prediction but rather serves as an interactive physical theory ...
Mingzi Sun +8 more
wiley +1 more source
Intelligent Supportive System for People with Profound Intellectual and Multiple Disabilities
A holistic INSENSION system is developed—a novel intelligent decision support system leveraging state‐of‐the‐art noninvasive audio‐visual sensor technologies together with machine learning algorithms and expert knowledge, to detect and interpret behaviors and communications (nonverbal signals—NVSs) of people with PIMD in challenging real‐world ...
Gašper Slapničar +10 more
wiley +1 more source
This study introduces a hydraulically steerable catheter with a soft tip in vascular procedures. The steering soft tip achieves a minimal diameter of 2.6 mm and supports a 180° bend. Real‐time shape and position tracking, facilitated by segmentation and endpoint detection techniques, improves navigation.
Jingyi Kang +9 more
wiley +1 more source
Use of fluoroquinolones and the risk of aortic and mitral regurgitation: A nationwide case-crossover study. [PDF]
Chou AH +10 more
europepmc +1 more source
Neuromorphic Device Based on Material and Device Innovation toward Multimode and Multifunction
In the era of big data, multimodal and multifunctional neuromorphic devices offer significant opportunities in designing AI hardware. In this work, recent advances about emerging material systems and novel device structures in this field are summarized in detail. Potential applications are reviewed.
Feng Guo +3 more
wiley +1 more source
Association between ambient temperature and economic burden of unintentional injury in Tianjin: a case-crossover study. [PDF]
Li Y +7 more
europepmc +1 more source

