Results 111 to 120 of about 161,419 (263)

Dual Encoder Contrastive Similarity for Legal Regulation Retrieval in Case-Based Reasoning

Journal of Applied Informatics and Computing
The increasing volume and complexity of legal regulations present challenges in retrieving relevant regulatory documents using conventional keyword-based approaches.
Adil Priman Hati Hulu, Anzas Ibezato Zalukhu   +1 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Applying the Case-Based Axiomatic Design Assistant (CADA) to a Pharmaceutical Engineering Task: Implementation and Assessment

Computers
Modern custom machine construction and automation projects face pressure to shorten innovation cycles, reduce durations, and manage growing system complexity.
Roland Wölfle, Irina Saur-Amaral, Leonor Teixeira   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Fuzzy case-based reasoning approach for finding COVID-19 patients priority in hospitals at source shortage period. [PDF]

Expert Syst Appl, 2021
Geetha S, Narayanamoorthy S, Manirathinam T, Kang D.   +3 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

An online optimization strategy for a fluid catalytic cracking process using a case-based reasoning method based on big data technology. [PDF]

RSC Adv, 2021
Ni P, Liu B, He G.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Using Case-Based Reasoning in a Learning System: A Prototype of a Pedagogical Nurse Tool for Evidence-Based Diabetic Foot Ulcer Care. [PDF]

J Diabetes Sci Technol, 2022
Bender C, Cichosz SL, Malovini A, Bellazzi R, Pape-Haugaard L, Hejlesen O.   +5 more
europepmc   +1 more source