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Designing Case-Control Studies [PDF]
Identification of confounding factors, evaluation of their influence on cause-effect associations, and the introduction of appropriate ways to account for these factors are important considerations in designing case-control studies. This paper presents designs useful for these purposes, after first providing a statistical definition of a confounding ...
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Combining controls can improve power in two-stage association studies
Background High dimensional case control studies are ubiquitous in the biological sciences, particularly genomics. To maximise power while constraining cost and to minimise type-1 error rates, researchers typically seek to replicate findings in a second ...
James Liley
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Association of Positive History of Pulmonary Tuberculosis with Female Infertility [PDF]
Background: The etiology of infertility has direct influence on the plan and outcome of its management. In this paper we showed the effect of history of tuberculosis (TB) on female infertility among infertile couples admitted to Royan infertility ...
babak eshrati +6 more
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Background: Metabolic syndrome (MS) has been associated with skin diseases such as psoriasis. They share a common inflammatory pathway and therefore have an impact on each other.
Akshay Samagani +2 more
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Individual correlates of podoconiosis in areas of varying endemicity: a case-control study [PDF]
BACKGROUND Podoconiosis is a non-filarial form of elephantiasis resulting in lymphedema of the lower legs. Previous studies have suggested that podoconiosis arises from the interplay of individual and environmental factors.
A Tora +48 more
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Risk of Guillain-Barré syndrome after 2010–2011 influenza vaccination [PDF]
Influenza vaccination has been implicated in Guillain Barré Syndrome (GBS) although the evidence for this link is controversial. A case–control study was conducted between October 2010 and May 2011 in seven Italian Regions to explore the relation between
Beghi, E +12 more
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Study design V. Case–control studies [PDF]
Previously in this series I have given an overview of the main types of study design and the techniques used to minimise biased results. In this article I describe more fully case control studies, their uses, advantages and limitations.
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Bypassing the selection rule in choosing controls for a case-control study
Objectives It has been argued that in case–control studies, controls should be drawn from the base population that gives rise to the cases. In designing a study of occupational injury and risks arising from long-term illness and prescribed medication, we
Coggon, David +2 more
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Improved branch and bound method for control structure screening [PDF]
The main aim of this paper is to present an improved algorithm of “Branch and Bound” method for control structure screening. The new algorithm uses a best- first search approach, which is more efficient than other algorithms based on depth-first search ...
Cao, Yi, Saha, Prabirkumar
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Background and aims: This cross-sectional observational case-control study was initiated in July 2016 with the aim of increasing an understanding of the underlying disease mechanisms in functional gastrointestinal disorders (FGIDs) including irritable ...
Phoebe Heenan +12 more
doaj +1 more source

