Results 71 to 80 of about 8,148,710 (302)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Case management training needs to support vocational rehabilitation for case managers and general practitioners: a survey study [PDF]

open access: yes, 2014
<b>Background</b><p></p> The use of the biopsychosocial model of health and case management for effective vocational rehabilitation (VR) has been confirmed for many health conditions. While Case and Condition Managers (CCMPs) use
Demou, Evangelia   +4 more
core   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

CONFLICT MANAGEMENT IN UNITED STATES AND IN BRAZIL

open access: yesRevista Eletrônica de Direito Processual, 2018
This paper presents a comparison between the system of conflict management in the US federal courts (Court Management and Case Management) with the conflict management model of the Brazilian civil procedural law, especially after the advent of the 2015 ...
Fernando da Fonseca Gajardoni
doaj   +1 more source

Foreign Exchange Risk Management Case Study: RJR NABISCO [PDF]

open access: yes, 1995
This article presents a case analysis of RJR Nabisco Holdings Corporation's foreign exchange management. The strategy pursued by RJR Nabisco, the two headed-hedging strategy succeded in lowering it's foreign exchange ...
Primanita, P. (Primanita)
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

An Evaluation of the Use and Effectiveness of Case Management in Clinical Nursing Education

open access: yesRisk Management and Healthcare Policy, 2021
Yu-Mei Liang,1 Jing-Yu Xie,1 Xiao-Hong Chen2 1Department of Nursing, Maoming People’s Hospital, Maoming, Guangdong Province, 525000, People’s Republic of China; 2Department of Neurosurgery, Maoming People’s Hospital, Maoming, Guangdong Province, 525000 ...
Liang YM, Xie JY, Chen XH
doaj  

Kajian Pengendalian Malaria di Provinsi Sumatera Utara dalam Upaya Mencapai Eliminasi Malaria

open access: yesJurnal Vektor Penyakit, 2018
North Sumatera province was the largest contributor to malaria positive cases for Sumatera island in 2016. This study aim was to analyze the malaria situation in North Sumatera, subsequently taken into consideration for the preparation of a strategic ...
Lukman Hakim   +2 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

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