Results 171 to 180 of about 4,052,768 (294)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Pulmonary Rheumatoid Nodules: A Case Report. [PDF]

Respirol Case Rep
Yuan M, Yin W, Wang L, Ye S.
europepmc   +1 more source

Case Reports

Journal of the College of Physicians and Surgeons Pakistan, 2019
openaire   +4 more sources

Case reports

Seizure, 2001
openaire   +3 more sources

Analysis and Codification of the Pre and Post Operative Anesthesia Related Tasks

Operations Research ...
Reisman, A. (Creatorcre), Lewy, P. (Creatorcre), Esogbue, A. (Creatorcre), Tamir, A. (Creatorcre), Kaujalgi, V. (Creatorcre)   +4 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Myopericarditis and leishmaniasis: a case report. [PDF]

Eur Heart J Case Rep
Cantos MB, Chango DX, Bravo J, Garcia-Zamora S, Baranchuk A.   +4 more
europepmc   +1 more source

Analysis of Runway Operations

Operations Research ...
Schrady, David A. (Creatorcre)
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Supersize panniculectomy: a case report. [PDF]

Int J Surg Case Rep
Uderzo S, Boffo R, Lo Sapio B, Nicoletti MM, Borriello A, Faenza M.   +5 more
europepmc   +1 more source