Results 251 to 260 of about 35,299,302 (406)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Case reports

Seizure, 2001
openaire   +3 more sources

Hemoptysis secondary to rupture of infected aortic aneurysm– a case report [PDF]

, 2019
Hina Inam, Ibrahim Zahid, Sarim Dawar Khan, Salman Ul Haq, Saulat Hasnain Fatimi   +4 more
openalex   +1 more source

High-Pressure Hand Injection Injury Case Report [PDF]

, 2020
Mangel, Patricia, Rometti, Mary
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Allopurinol-Induced Lymphadenopathy: A Case Report. [PDF]

ACR Open Rheumatol
Harata M, Das A.
europepmc   +1 more source

Angiosarcoma (Stewart-Treves syndrome) in postmastectomy patients: report of 10 cases and review of literature.

, 2015
Lifang Cui, Jixin Zhang, Xinmin Zhang, Hong Chang, Congling Qu, Jianying Zhang, Dingrong Zhong   +6 more
openalex   +1 more source

Metastatic Hurthle Cell Carcinoma of the thyroid presenting as a Breast Lump: A Case Report [PDF]

, 2008
Yahya Al-Abed, Emma V. Gray, Konrad Wolfe, G. W. R. Watters, Jonathan M. Philpott   +4 more
openalex   +1 more source

Can betamethasone prevent Nicolau syndrome when coadministered with penicillin? A case report

, 2021
Paria Mojarrad, Behnaz Barikbin, Mohammad Bagher Oghazian   +2 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source