Results 281 to 290 of about 35,299,302 (406)

Case Report: Creutzfeldt-Jakob disease and diagnosis challenges: case report and evidence synthesis. [PDF]

F1000Res
Failoc Rojas VE, Yazawa-Ballena Y, Alvarado-Moreno G, Navarro-Flores A, Alva-Diaz C, Pacheco-Barrios K.   +5 more
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Lightning-Induced Keraunoparalysis and Rhabdomyolysis: A Case Report. [PDF]

Clin Case Rep
Bhattarai S, Baral S, Joshi KC.
europepmc   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Late Ebola virus relapse causing meningoencephalitis: a case report

The Lancet, 2016
M. Jacobs, A. Rodger, D. Bell, S. Bhagani, I. Cropley, A. Filipe, Robert J Gifford, S. Hopkins, J. Hughes, Farrah Jabeen, I. Johannessen, D. Karageorgopoulos, A. Lackenby, Rebecca Lester, Rebecca S N Liu, A. Macconnachie, T. Mahungu, Daniel Martín, N. Marshall, S. Mepham, R. Orton, Massimo Palmarini, M. Patel, C. Perry, S. E. Peters, D. Porter, David Ritchie, N. Ritchie, R. A. Seaton, Vattipally B. Sreenu, K. Templeton, Simon Warren, G. Wilkie, Maria Zambon, R. Gopal, E. Thomson   +35 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A Rare Presentation of Crohn's Disease: A Case Report. [PDF]

Cureus
Marques Ferreira I, Coelho R, Cruz C, Ferreira Henriques I, Ribeiro S.   +4 more
europepmc   +1 more source

Poorly differentiated cecal adenocarcinoma showing prominent rhabdoid feature combined with appendiceal mucinous cystadenoma: A case report and review of the literature

, 2015
IN-JU CHO, SUNG-SOO KIM, YOUNG-DON MIN, MUN-WHAN NOH, Ran Hong   +4 more
openalex   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source