Results 61 to 70 of about 34,993,028 (405)

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Hepatic Sarcoidosis Presenting as Cholestatic Liver Injury Exacerbated by Nitrofurantoin Use

open access: yesTranslation, 2023
Please view the PDF to see the formatted meeting abstract.  
Sean J Halloran
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Basics of case report form designing in clinical research

open access: yesPerspectives in Clinical Research, 2014
Case report form (CRF) is a specialized document in clinical research. It should be study protocol driven, robust in content and have material to collect the study specific data.
Shantala Bellary   +2 more
doaj   +1 more source

Recurrent Pancreatitis Secondary to Common Channel Volvulus through Petersen’s Space Defect in a Patient with Roux-En-Y Bypass

open access: yesTranslation, 2023
Please view the PDF to see the formatted meeting abstract.  
Anas Renno
doaj   +1 more source

Amyand’s hernia : a case report [PDF]

open access: yes, 2013
The presence of vermiform appendix, whether normal or inflamed in the inguinal hernia, is referred to as Amyand’s hernia. This is rare occurring in about 1% of inguinal hernias in adults.
Muscat, Peter
core  

First Case of 2019 Novel Coronavirus in the United States

open access: yesNew England Journal of Medicine, 2020
Summary An outbreak of novel coronavirus (2019-nCoV) that began in Wuhan, China, has spread rapidly, with cases now confirmed in multiple countries.
Michelle L. Holshue   +23 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Kienböck’s Disease: Case Report - Case Report

open access: yesTürk Osteoporoz Dergisi, 2009
Osteonecrosis is defined as the death of bone due to interruption of the blood supply to the bone. Kienböck’s disease is osteonecrosis of lunate bone as a result of heavy repetitive loading on wrist.
Hayal Güler   +3 more
doaj  

Rare Occurrence of Primary Gastric Lymphoma:

open access: yesTranslation, 2023
Please view the PDF to see the formatted meeting abstract.  
Meghana Ranabothu
doaj   +1 more source

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