Results 101 to 110 of about 7,398,686 (294)

Alaska Trial Court Case Filing Statistics, 2005–2012 [PDF]

open access: yes, 2013
This fact sheet describe case filings, caseloads, and types of cases filed in Alaska’s trial courts (Superior Court and District Court) during fiscal years (FY) 2005–2012. Data were extracted from Alaska Court System annual statistical reports.
Fortson, Ryan, Myrstol, Brad A.
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Getting to good: how headteachers achieve success [PDF]

open access: yes, 2012
This report examines the key steps taken by headteachers in schools that have improved from satisfactory to good or better. It draws on evidence from good practice case study visits, headteacher focus group meetings and previous Ofsted survey reports ...

core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Recruiting Lower-Income Women into Information Technology Careers: Building a Foundation for Action [PDF]

open access: yes, 2002
This report makes the case for encouraging more low-wage women to consider careers in information technology. It assesses women's knowledge and perceptions about the IT field and establishes a framework to promote opportunities in IT.
Davis Jenkins   +4 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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