Results 131 to 140 of about 30,877,029 (400)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Marghera Garden City Piazza del Mercato, The ‘Area Gasometri’, Bovisa, Milan, and The Riviera del Brenta [PDF]

open access: yes, 2018
This report summarises the findings of the JPI Heritage Plus PICH Project’s investiga¬tion of the impact of the reform of urban planning on the histor¬ic built environment.
Fontanari, Enrico   +2 more
core  

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

The voice of the child: learning lessons from serious case reviews’ [PDF]

open access: yes, 2011
This report provides an analysis of 67 serious case reviews that Ofsted evaluated between 1 April and 30 September 2010. The main focus of the report is on the importance of listening to the voice of the child.

core  

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

LexGenie: Automated Generation of Structured Reports for European Court of Human Rights Case Law [PDF]

open access: yesarXiv
Analyzing large volumes of case law to uncover evolving legal principles, across multiple cases, on a given topic is a demanding task for legal professionals. Structured topical reports provide an effective solution by summarizing key issues, principles, and judgments, enabling comprehensive legal analysis on a particular topic.
arxiv  

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