Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi+3 more
wiley +1 more source
Marghera Garden City Piazza del Mercato, The ‘Area Gasometri’, Bovisa, Milan, and The Riviera del Brenta [PDF]
This report summarises the findings of the JPI Heritage Plus PICH Project’s investiga¬tion of the impact of the reform of urban planning on the histor¬ic built environment.
Fontanari, Enrico+2 more
core
FAMILIAL PRESENILE DEMENTIA: REPORT OF CASE WITH CLINICAL AND PATHOLOGICAL FEATURES OF ALZHEIMER'S DISEASE [PDF]
W. H. McMenemey+3 more
openalex +1 more source
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker+14 more
wiley +1 more source
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen+13 more
wiley +1 more source
The voice of the child: learning lessons from serious case reviews’ [PDF]
This report provides an analysis of 67 serious case reviews that Ofsted evaluated between 1 April and 30 September 2010. The main focus of the report is on the importance of listening to the voice of the child.
core
THE SURGICAL ASPECTS OF MAJOR NEURALGIA OF THE TRIGEMINAL NERVE.A REPORT OF TWENTY CASES OF OPERATION ON THE GASSERIAN GANGLION, WITH ANATOMIC AND PHYSIOLOGIC NOTES ON THE CONSEQUENCES OF ITS REMOVAL. [PDF]
Harvey Cushing
openalex +1 more source
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha+6 more
wiley +1 more source
LexGenie: Automated Generation of Structured Reports for European Court of Human Rights Case Law [PDF]
Analyzing large volumes of case law to uncover evolving legal principles, across multiple cases, on a given topic is a demanding task for legal professionals. Structured topical reports provide an effective solution by summarizing key issues, principles, and judgments, enabling comprehensive legal analysis on a particular topic.
arxiv