Results 171 to 180 of about 2,907,863 (245)
Editorial: Case reports in psychopharmacology, volume IV. [PDF]
Front PsychiatryStuhec M, Di Ciano P.
europepmc +1 more source
Case reports in the past, present and future
European Journal of Case Reports in Internal MedicineJohn G. Kellett
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Capsule retention in Crohn's disease requiring surgical management: two case reports. [PDF]
J Surg Case RepKhyat C, Salihoun M, Serraj I, Kabbaj N.
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Perianesthetic Complications in Genetic Mitochondrial Disease: A Review of Case Reports. [PDF]
Paediatr AnaesthJohnson BM, Johnson SC.
europepmc +1 more source