Results 201 to 210 of about 8,204,523 (309)

Focus on Valvular Heart Disease and Structural Interventions

JACC: Case Reports, 2020
Julia Grapsa, MD, PhD
doaj   +1 more source

<i>Globicatella sanguinis</i>-A Literature Review of Case Reports. [PDF]

Medicina (Kaunas)
Rîpă CV, Cobzaru RG, Iancu LS, Rîpă MR, Popescu G, Maștaleru A, Oancea A, Leon MM.   +7 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Sarcoidosis-like cutaneous lesions in paracoccidioidomycosis: four case reports and review of the literature. [PDF]

An Bras Dermatol
Ribeiro JS, Stelini RF, Magalhães RF, Velho PENF, França AFEDC.   +4 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Retracted: Extreme Anemia (Hemoglobin 1.8 g/dL) Secondary to Abnormal Uterine Bleeding

Case Reports in Obstetrics and Gynecology, 2019
Case Reports in Obstetrics and Gynecology
doaj   +1 more source

Editorial: Case reports in breast cancer 2023-2024. [PDF]

Front Oncol
Yan F, Sun M, Kaplan H.
europepmc   +1 more source

Adenomatoid Odontogenic Tumor – A Report of Two Cases with Histopathology Correlation

, 2011
Pavitra Baskaran, Satya Ranjan Misra, M Sathyakumar, R. Mithra   +3 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Retracted: Prenatal Diagnosis of Concurrent Achondroplasia and Klinefelter Syndrome

Case Reports in Obstetrics and Gynecology, 2016
Case Reports in Obstetrics and Gynecology
doaj   +1 more source