Results 271 to 280 of about 8,253,745 (359)
Evaluation of intelligent exploitation tools for unstructured police case reports. [PDF]
De Beer, Jan +3 more
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Malignant mesothelioma in rare sites: two case reports. [PDF]
Du Q +7 more
europepmc +1 more source
Arachnoid Cyst Causing Depression and Neuropsychiatric Symptoms: a Case Report
Manoj Shettar +5 more
openalex +2 more sources
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Rare Mucinous Tumors of the Alveolar Space: Two Case Reports. [PDF]
Sha C, Esposito M, Lee PC.
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Peritumoral Cystic Meningioma With Diagnostic Challenges: Two Case Reports and a Literature Review. [PDF]
Chen WC, Lin ZJ, Chee-Tat L.
europepmc +1 more source

