Results 101 to 110 of about 93,544 (180)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Neodržavanje u ispravnom stanju brodske opreme : (prikaz presude)
Poredbeno Pomorsko Pravo, 2006 Brod ne smije isploviti bez odgovarajuće opreme. Oprema mora biti u ispravnom stanju, a rok njezine valjanosti bitan je činitelj njezine ispravnosti.
Vesna Skorupan
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Pravo trećih da svoja potraživanja ostvaruju u arbitražnom postupku : (prikaz presude)
Poredbeno Pomorsko Pravo, 2006 Iako broker nije ugovorna strana u ugovoru o iskorištavanju broda, pa time ni u arbitražnom sporazumu sadržanom u takvom ugovoru, ovlašten je i obvezan ostvarivati svoje pravo na plaćanje brokerske provizije pokretanjem arbitražnog postupka protiv ...
Zoran Tasić
doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Zaustavljanje broda radi osiguranja potraživanja s naslova prodaje broda : [prikaz presude]
Uporedno pomorsko pravo, 1991 Za ovo zaustavljavljanje broda primjenjuju se odredbe Zakona o pomorskoj i unutrašnjoj plovidbi. Ukoliko se radi o objektima koji se ne smatraju brodovima, primjenjuju se propisi općeg iszvršnog postupka. Da bi zahtjev za zaustavljanje broda bio opravdan,
Pave Dević
doaj
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Ograničenje brodarove odgovornosti - Osnivanje fonda odgovornosti : [prikaz presude]
Uporedno pomorsko pravo, 1990 Kada je osnovan fond ograničene odgovornosti, postupak se provodi prema Zakonu o pomorskoj i unutrašnjoj plovidbi, a ne prema Zakonu o izvršnom postupku.
Veljko Vujović
doaj
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source