Results 131 to 140 of about 44,295,395 (243)
Modos de intervir com jovens deficientes visuais: dois estudos de caso
Este trabalho investiga as relações entre corpo e cognição entre jovens deficientes visuais. Dois estudos de caso são apresentados, fundamentados em contribuições da pesquisa ação-crítica e da teoria ator-rede.
Marcia Moraes
doaj
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
El incremento de poder (empowerment en ingles) es un constructo complejo asociado con varios significados, pasos y acciones. Dunst, Trivette, y LaPointe (1992) proponen un marco teórico que integra tres componentes del incremento de poder: ideología ...
JHON J SANABRIA,, FABRICIO BALCAZAR
doaj
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Identifying Dose-Relevant Covariates With SCOUT: A Case Study of Lorlatinib. [PDF]
Ideno Y.
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Advanced study pieces for the pianoforte
For piano Edited by various editors Pattering raindrops: staccato etude, Op. 83, No. 1 / Wilson G. Smith -- By the sea = Am Strande, Op. 8, No. 2 / George Posca -- Etude de concert, Op. 8, no. 1 / F.J. McDonough -- Spring zephyrs: octave etude, Op.
Scriabin, Aleksandr Nikolayevich,1872-1915 (Creatorcre) +15 more
core
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source

