Results 171 to 180 of about 20,150,065 (344)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
"Disability data: a case study in research limitation transparency": a response. [PDF]
Mitra S.
europepmc +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Behçet Disease and Cognitive Impairment: A Case Study of an Overlooked Symptom. [PDF]
Nathania CE +7 more
europepmc +1 more source
Calcium intake and factors associated with the use of calcium supplements; a case study in Maharagama Divisional Secretarial Division, Colombo District [PDF]
A.T. Andrahennadi
openalex +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
A Giant Basal Cell Carcinoma of the Scalp-A Clinical Case Study. [PDF]
Zagórska B +6 more
europepmc +1 more source

