Results 211 to 220 of about 20,150,065 (344)

case study [PDF]

, 2015
Faganel, Armand, Trnavčevič, Anita
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The relevance and use of information and telecommunication networks as strategic tools in the transport sector: a Dutch case study

, 1996
Peter Nijkamp, Gerard Pepping
openalex   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Revision Distal Bicep Repair in the Setting of Heterotopic Ossification: Case Study. [PDF]

Clin Case Rep
Brikho AM, Abbo JJ, Yousif MJ.
europepmc   +1 more source

Relation Of The Arm Profile Score And The Linear Index Of Function. Is The Shap An Adequate Functionality Assessment Of Prosthetic Use? A Case Study

, 2018
Fabian Unglaube, Barbara Pobatschnig, Andreas Kranzl   +2 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Editorial: Using case study and narrative pedagogy to guide students through the process of science

Frontiers in Microbiology
Davida S. Smyth, Pat Marsteller, Courtney Carroll Alexander, Alex L. Deal, Carlos C. Goller   +4 more
doaj   +1 more source

Complexities of Bartter Syndrome Type III: A Case Study in Jordan. [PDF]

Oxf Med Case Reports
Hanifa H, Al-Badareen Y, Al-Refaai MM, Ganama NM, Alabrash MS, Alsaleh B.   +5 more
europepmc   +1 more source

Marketing Innovation Implementation : A case study of a Chinese Pharmaceutical Company

, 2010
Xiaoshuang Pang, Yunpeng Qu
openalex   +1 more source