Results 61 to 70 of about 76,107,248 (332)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Carbon Taxes and CO2 Emissions: Sweden as a Case Study

open access: yesAmerican Economic Journal: Economic Policy, 2019
This quasi-experimental study is the first to find a significant causal effect of carbon taxes on emissions, empirically analyzing the implementation of a carbon tax and a value-added tax on transport fuel in Sweden.
J. Andersson
semanticscholar   +1 more source

Radiative damping: a case study

open access: yes, 2011
We are interested in the motion of a classical charge coupled to the Maxwell self-field and subject to a uniform external magnetic field, B. This is a physically relevant, but difficult dynamical problem, to which contributions range over more than one ...
Abraham M   +12 more
core   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

"Lumen": A Case Study on Domestic Violence

open access: yesJPAIR, 2009
A case study was done on"Lumen" a wife who is a victim of domestic violence with the husband as the perpetrator. Utilizing narrative analysis, findings, as supported by the propositions of Sociological Functionalist and Feminist Theories, revealed that ...
Fleoy Ysmael
doaj   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Case Study Analysis for Sector Research and Teaching Support

open access: yesInternational Journal on Food System Dynamics, 2016
The use of case studies in dealing with problems of the food sector is gaining increasingly attention in the scientific community. Case-based reasoning supports as a scientific approach the analysis of problems, relationships, behavior, and development ...
Gerhard Schiefer
doaj   +1 more source

Case study: Class diagram restructuring

open access: yes, 2013
This case study is an update-in-place refactoring transformation on UML class diagrams. Its aim is to remove clones of attributes from a class diagram, and to identify new classes which abstract groups of classes that share common data features.
Lano, K., Rahimi, S. Kolahdouz
core   +2 more sources

Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study.

open access: yesThe Lancet, 2004
BACKGROUND Although more than 80% of the global burden of cardiovascular disease occurs in low-income and middle-income countries, knowledge of the importance of risk factors is largely derived from developed countries.
S. Yusuf   +10 more
semanticscholar   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel   +3 more
wiley   +1 more source

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