Results 71 to 80 of about 91,991,955 (298)

Comparative Case Studies

open access: yesEducação & Realidade, 2017
What is a case study and what is it good for? In this article, we review dominant approaches to case study research and point out their limitations. Next, we propose a new approach – the comparative case study approach – that attends simultaneously to ...
Lesley Bartlett, Frances Vavrus
doaj  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Towards More Case Study Research in Entrepreneurship [PDF]

open access: yesTechnology Innovation Management Review, 2012
Entrepreneurship as an emerging discipline has made good strides, but according to some, has fallen short of bringing its theory and literature up to the standards of others in the management sciences.
Tom Duxbury
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Case Study Research: Foundations and Methodological Orientations

open access: yesForum: Qualitative Social Research, 2017
Over the last forty years, case study research has undergone substantial methodological development. This evolution has resulted in a pragmatic, flexible research approach, capable of providing comprehensive in-depth understanding of a diverse range of ...
Helena Harrison   +3 more
doaj  

Beating the Odds! Build theory from emerging markets phenomenon and the emergence of case study research—A “Test-Tube” typology

open access: yesCogent Business & Management, 2015
The extant social sciences and management theoretical concepts and empirical literature have mostly determined based on western (developed) economies institutional context. In the recent past, a number of researchers have argued that the western theories
Kotapati Srinivasa Reddy
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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