(-)-T-Cadinol—A Sesquiterpene Isolated From Casearia sylvestris (Salicaceae)—Displayed in Vitro Activity and Causes Hyperpolarization of the Membrane Potential of Trypanosoma cruzi [PDF]
Frontiers in Pharmacology, 2021 Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and affects 6–8 million people worldwide, mainly from developing countries. The treatment is limited to two approved nitro-derivatives, nifurtimox and benznidazole, with several side ...
Joao Henrique G Lago +2 more
exaly +5 more sources
Seasonal and Circadian Rhythms of Clerodane Diterpenes and Glycosylated Flavonoids in Two Varieties of Casearia sylvestris Sw. (Salicaceae) [PDF]
HeliyonCasearia sylvestris Sw. (Salicaceae) is noted for its morphological and chemical plasticity and pharmacological properties. The present study investigates two of its varieties: C. sylvestris var.
Alberto José Cavalheiro +2 more
exaly +5 more sources
Anti-Inflammatory, Antioxidant, and Reparative Effects of Casearia sylvestris Leaf Derivatives on Periodontium In Vitro [PDF]
AntioxidantsGingival inflammation compromises the integrity of the gingival epithelium and the underlying tissues, highlighting the need for adjuvant therapies with immunomodulatory and healing properties.
Angélica L. R. Pavanelli +8 more
doaj +3 more sources
Antimicrobial and antibiofilm activities of Casearia sylvestris extracts from distinct Brazilian biomes against Streptococcus mutans and Candida albicans [PDF]
BMC Complementary and Alternative Medicine, 2019 Background Dental caries is a biofilm-diet-dependent worldwide public health problem, and approaches against microorganisms in cariogenic biofilms are necessary.
Sabrina M. Ribeiro +6 more
doaj +3 more sources
Antileishmanial activity of Melampodium divaricatum and Casearia sylvestris essential oils on Leishmania amazonensis [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 2019 Leishmaniasis is a disease that affects millions of people and it is an important public health problem. The drugs currently used for the treatment of leishmaniasis present undesirable side effects and low efficacy.
Raquel Regina Duarte Moreira +8 more
doaj +3 more sources
Effect of Extracts, Fractions, and Isolated Molecules of Casearia sylvestris to Control Streptococcus mutans Cariogenic Biofilm. [PDF]
Antibiotics (Basel), 2023 The effects of extracts, fractions, and molecules of Casearia sylvestris to control the cariogenic biofilm of Streptococcus mutans were evaluated. First, the antimicrobial and antibiofilm (initial and pre-formed biofilms) in prolonged exposure (24 h ...
Ribeiro SM +3 more
europepmc +2 more sources
Corrigendum: (-)-T-Cadinol, a Sesquiterpene Isolated From Casearia sylvestris (Salicaceae)-Displayed In Vitro Activity and Causes Hyperpolarization of the Membrane Potential of Trypanosoma cruzi. [PDF]
Front Pharmacol, 2022 [This corrects the article DOI: 10.3389/fphar.2021.734127.].
Dos Santos AL +5 more
europepmc +2 more sources
Orbital: The Electronic Journal of Chemistry, 2022 Casearia sylvestris var. lingua (Cambess.) Eichler is widely used in traditional medicine to treat diseases. Simultaneously, the growing search for phytocosmetics has culminated in the exploration of plant extracts.
Claudia Andrea Lima Cardoso +3 more
doaj +2 more sources
Mapping the Technological and Pharmacological Landscape of Casearia sylvestris: An Evidence-Based Prospection for Wound Healing and Pain Management. [PDF]
Chem BiodiversCasearia sylvestris Sw. (Salicaceae) is a South American medicinal plant traditionally used for the treatment of inflammatory conditions, pain, and wound healing, with its biological activity mainly attributed to clerodane diterpenes and flavonoids. This
Soutier LG +10 more
europepmc +2 more sources
Casearia sylvestris Derivatives Inhibit Inflammation and Oxidative Activity and Promote Healing in Human Gingival Fibroblasts - An In Vitro Study. [PDF]
Oral Health Prev DentPurpose New promising adjuvant approaches for managing periodontal inflammation are emerging. Casearia sylvestris, a medicinal plant rich in diterpenes, has demonstrated anti-inflammatory, antioxidant, and reparative properties.
Pavanelli ALR +9 more
europepmc +2 more sources