Results 211 to 220 of about 154,747 (344)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Design and Experimental Study on Casing Pipe Continuous Flow Cryostat System

open access: bronze, 2019
Changli Sun   +4 more
openalex   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Spontaneous passage of an accidentally ingested metallic bullet casing in an adolescent: a case report. [PDF]

open access: yesInt J Emerg Med
Nur Iyow S   +4 more
europepmc   +1 more source

NMR spectroscopy of coin cell batteries with metal casings

open access: green, 2021
Brennan J. Walder   +8 more
openalex   +1 more source

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