Results 151 to 160 of about 11,840,309 (376)

Detailed flow measurements in casing boundary layer of 429-meter-per-second-tip-speed two-stage fan [PDF]

open access: yes
Detailed flow measurements between all blade rows were taken in the outer 30 percent of passage height of a two stage fan. Tabulations of the detailed flow measurements are included.
Gorrell, W. T.
core   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Population dynamics of mushroom casing over the course of Agaricus bisporus cultivation in the presence of Bacillus velezensis QST 713 and Bacillus velezensis Kos biocontrol agents

open access: yesBiological Control
The globally cultivated white button mushroom (Agaricus bisporus) is grown commercially at an industrial scale. Numerous pathogens pose a significant economic threat to its cultivation. Due to the emergence of resistance towards fungicide treatments, the
Joy Clarke   +3 more
doaj   +1 more source

An Evaluation of Passive Wall Treatment With Circumferential Grooves at the Casing of the First and Second Blade Rotor Rows of a High-performance Multi-stage Axial Compressor [PDF]

open access: green, 2023
Rubén Bruno Díaz   +4 more
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Alaskan water resources: Selected abstracts, 1974 [PDF]

open access: yes, 1977
Compiled and Edited by Charles Hartman and Sheila. FinchAs one of the 51 Water Resources Research Institutes administered under the Water Resources Research Act of 1964, IWR receives a semimonthly journal entitled Selected Water Resources Abstracts.
Finch, Sheila, Hartman, Charles
core  

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

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