Results 151 to 160 of about 7,266 (305)

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Research and Field Test of Sand and Rock Influx Well Control Technology

Shiyou jixie
To address the challenges such as incomplete sand flushing， poor sand consolidation and blockage failure during casing damaged sand and rock influx well control process， a set of comprehensive treatment technical scheme was proposed， including ...
Dong Lei, Wang Zheng, Lin Qingxiang, Li Fucai, Gao Zuoyu, Ma Shengkai, Zhang Yongchun   +6 more
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Effects of tip clearance on overall performance of transonic fan stage with and without casing treatment

, 1977
The overall performance of a transonic fan stage is presented for various tip clearances, with and without casing treatment. The stage was tested with a solid casing, and with open skewed slots and closed skewed slots in the casing over the rotor blade ...
Osborn, W. M., Moore, R. D.
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Effect of casing treatment on performance of an inlet stage for a transonic multistage compressor

, 1976
An inlet stage of a transonic compressor was tested with three rotor tip casing treatment configurations: blade angle slots, circumferential grooves, and axial skewed slots.
Urasek, D. C., Moore, R. D., Lewis, G. W., Jr.   +2 more
core  

Study on the stability enhancement mechanism of a high-speed axial compressor under paired swirl distortion. [PDF]

Sci Rep
Cheng B, Li Y, Yin Z, Yu Y, Liu J.
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Self-Recirculating Casing Treatment Concept for Enhanced Compressor Performance

, 2002
A state-of-the-art CFD code (APNASA) was employed in a computationally based investigation of the impact of casing bleed and injection on the stability and performance of a moderate speed fan rotor wherein the stalling mass flow is controlled by tip flow
Hathaway, Michael D.
core  

Recycling Zn Casing Waste into a ZnO-Cu-Based Electrocatalyst for Selective CO₂ Electroreduction to Ethylene. [PDF]

ACS Omega
Pittayavinai P, Inudom T, Kasemchainan J, Poompradub S.   +3 more
europepmc   +1 more source