Results 191 to 200 of about 11,840,309 (376)
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee+9 more
wiley +1 more source
Numerical Modeling of Wellbore and Formation Temperature Recovery Prior to Cementing Operations. [PDF]
Feng B+7 more
europepmc +1 more source
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima+6 more
wiley +1 more source
Using spent mushroom substrate (SMS) as a casing boosted bacterial activity and enhanced the mineral profile of the Calocybe indica. [PDF]
Bashir R+7 more
europepmc +1 more source
Study of unconventional aircraft engines designed for low energy consumption [PDF]
A study of unconventional engine cycle concepts, which may offer significantly lower energy consumption than conventional subsonic transport turbofans, is described herein.
Hirschkron, R.+2 more
core +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Heat-Treated Sucuk in Natural Casings: A Source of Higher Fermentative and Oxidative Volatile Compounds? [PDF]
Dursun A, Türkmen D, Güler Z.
europepmc +1 more source
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova+26 more
wiley +1 more source
Recyclability of Plastics from Waste Mobile Phones According to European Union Regulations REACH and RoHS. [PDF]
Bruno M, Fiore S.
europepmc +1 more source