Results 331 to 337 of about 341,145 (337)
Some of the next articles are maybe not open access.
Kanamycin activates caspase-1 in NC/Nga mice
Experimental Dermatology, 2011Abuse of antibiotics to treat children has been associated with an increased risk of the development of inflammatory diseases. The underlying mechanism behind this association still remains to be clarified. Here, we examined the mechanisms behind kanamycin-induced skin inflammation in NC/Nga mice.
Hyun-Ja Jeong, Na-Ra Han, Hyung-Min Kim
openaire +3 more sources
Is caspase 1 central to activation of interleukin-1?
Joint Bone Spine, 2011Joint Bone Spine - In Press.Proof corrected by the author Available online since dimanche 3 avril ...
Miriam Wittmann +2 more
openaire +3 more sources
Annals of Neurology, 2002
AbstractCaspase 1 plays a pivotal role in generating mature cytokine interleukin‐1β. Interleukin‐1β is implicated as a mediator of pneumococcal meningitis, both in experimental models and in humans. We demonstrated here that (1) Caspase 1 mRNA and protein expression is upregulated in the brain during experimental pneumococcal meningitis, and (2 ...
Richard A. Flavell +5 more
openaire +3 more sources
AbstractCaspase 1 plays a pivotal role in generating mature cytokine interleukin‐1β. Interleukin‐1β is implicated as a mediator of pneumococcal meningitis, both in experimental models and in humans. We demonstrated here that (1) Caspase 1 mRNA and protein expression is upregulated in the brain during experimental pneumococcal meningitis, and (2 ...
Richard A. Flavell +5 more
openaire +3 more sources
Brain Research, 2001
The localization of caspase-1 protein, interleukin-1beta (IL-1beta)-converting enzyme, was immunohistochemically examined in the hippocampal CA-1 subfield by a transient occlusion of bilateral common carotid arteries in Mongolian gerbils. Immunoreactivities for caspase-1 were found in microglias, astrocytes, endothelial cells of capillaries and some ...
Mitsuyo Maeda +7 more
openaire +3 more sources
The localization of caspase-1 protein, interleukin-1beta (IL-1beta)-converting enzyme, was immunohistochemically examined in the hippocampal CA-1 subfield by a transient occlusion of bilateral common carotid arteries in Mongolian gerbils. Immunoreactivities for caspase-1 were found in microglias, astrocytes, endothelial cells of capillaries and some ...
Mitsuyo Maeda +7 more
openaire +3 more sources
The protease caspase-1: Activation pathways and functions
Biochemical and Biophysical Research CommunicationsCaspase-1 is one of the main mediators of inflammatory caspases and has become a correspondent with inflammation, cell death, and several inflammatory diseases. In this review, we systematically summarize both original and recent advances in caspase-1 to provide references for a better understanding of the molecular mechanisms in its activation and ...
Hongmin, Zhen +4 more
openaire +2 more sources