Results 301 to 310 of about 160,266 (354)

Roles of Pyroptosis in the Progression of Pulpitis and Apical Periodontitis. [PDF]

open access: yesJ Inflamm Res
Gu F   +7 more
europepmc   +1 more source

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

open access: yesAdvanced NanoBiomed Research, EarlyView.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska   +2 more
wiley   +1 more source

Graphene Oxide‐Based Gene Modulation in Preferential Elimination of Lung Cancer Cells in a 3D Tumor Microenvironment Model

open access: yesAdvanced NanoBiomed Research, EarlyView.
Chemically modified graphene oxide nanocarriers provide a targeted lung cancer gene therapy platform. In a 3D tumor microenvironment model, these nanocarriers deliver therapeutic genes, regulate immune markers, and induce apoptosis in cancer cells. Combined gene delivery enhances cancer cell elimination, demonstrating the potential of this approach for
Francesca Grilli   +3 more
wiley   +1 more source

An activation-based high throughput screen identifies caspase-10 inhibitors. [PDF]

open access: yesRSC Chem Biol
Castellón JO   +10 more
europepmc   +1 more source

Immunoengineering eines Photocage‐geschützten 5′‐Triphosphat‐Oligoribonukleotid‐Liganden zur spatiotemporalen Kontrolle der RIG‐I‐Aktivierung bei Tumoren

open access: yesAngewandte Chemie, EarlyView.
In dieser Studie wird eine Methode zur präzisen Kontrolle von Retinsäure‐Induzierbaren‐Gens‐I (RIG‐I) vorgestellt, einem Rezeptor des angeborenen Immunsystems, der, wenn er aktiviert wird, antitumorale Immunreaktionen und Zelltod von Krebszellen auslöst.
Sandra Anika Lewash   +11 more
wiley   +1 more source

Immunoengineering of a Photocaged 5´‐triphosphate Oligoribonucleotide Ligand for Spatiotemporal Control of RIG‐I Activation in Cancer

open access: yesAngewandte Chemie International Edition, EarlyView.
This study presents a method for precise control of RIG‐I (retinoic acid inducible gene I), an innate immune receptor of RNA that, when activated, induces anti‐tumor immune responses and cancer cell death. By incorporating photocage modifications into RNA ligands, we enable a spatially and temporally regulated immune response and offer a targeted ...
Sandra Anika Lewash   +11 more
wiley   +1 more source

Melatonin as a treatment for atherosclerosis: focus on programmed cell death, inflammation and oxidative stress. [PDF]

open access: yesJ Cardiothorac Surg
Asemi R   +5 more
europepmc   +1 more source

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