Results 91 to 100 of about 13,750 (216)

Toward Anti‐Herpesviral PROTACs: Assessing the Challenges for Targeted Protein Degradation on the Example of Kaposi's Sarcoma‐Associated Herpesvirus Latency‐Associated Nuclear Antigen

open access: yesChemMedChem, Volume 21, Issue 1, January 2026.
It is attempted to employ proteolysis‐targeting chimeras‐based targeted protein degradation to the viral protein “Latency‐associated Nuclear Antigen” from Kaposi's sarcoma‐associated herpesvirus. While ternary complex formation is detected via native mass spectrometry, protein degradation is not observed, presumably due to insufficient permeability ...
Aylin Berwanger   +10 more
wiley   +1 more source

Diagnostic challenges in patients with Castleman disease, a single center experience from Hungary

open access: yesPathology and Oncology Research
Castleman disease is a rare and atypical lymphoproliferative disorder characterized by diverse clinical manifestations. It has both unicentric and multicentric forms, the latter with further subdivisions, i.e., human herpesvirus 8-associated and ...
Boglárka Brúgós   +6 more
doaj   +1 more source

A Case of IgG4‐Related Disease That Mimics an Anterior Mediastinal Malignant Tumour

open access: yesRespirology Case Reports, Volume 14, Issue 1, January 2026.
We describe a rare case of IgG4‐related disease presenting as an anterior mediastinal mass mimicking malignancy. This case demonstrates the importance of considering IgG4‐related disease in the differential diagnosis of mediastinal tumours, even when FDG‐PET shows abnormal accumulation and serum IgG4 levels are not particularly high.
Noriaki Nishimura   +12 more
wiley   +1 more source

A rare case report of hyaline-vascular type Castleman disease in the presacral region

open access: yesFrontiers in Oncology
Castleman disease (CD), also known as giant lymph node hyperplasia or angiofollicular lymph node hyperplasia, is a rare and indeterminate group of chronic lymphoproliferative disorders.
Long Chang   +4 more
doaj   +1 more source

Polymorphic Mucocutaneous Eruption and Septic Shock in a 75‐Year‐Old Man

open access: yes
JEADV Clinical Practice, Volume 5, Issue 1, Page 323-325, March 2026.
Sweta Subhadarshani   +2 more
wiley   +1 more source

Core Needle Biopsies in Patients With Lymphoproliferative Malignancies: An Observational Single‐Center Cohort Study

open access: yesEuropean Journal of Haematology, Volume 116, Issue 1, Page 85-92, January 2026.
ABSTRACT In the diagnostic evaluation of suspected lymphoma, both core needle biopsy (CNB) and surgical excisional biopsy (SEB) are routinely employed for tissue sampling. While SEB remains the gold standard, CNB is a less invasive and more cost‐effective alternative. However, concerns persist regarding its diagnostic yield.
Blas Holger Mogensen   +5 more
wiley   +1 more source

Castleman Disease in the Pediatric Neck: Case Report and Literature Review [PDF]

open access: yes, 2013
Objective: To investigate the common features of cervical pediatric Castleman disease (CD). Study Design: Case report and literature review of pediatric patients with cervical CD.
Conard, MD, Katrina   +3 more
core   +1 more source

Using a smartphone app to identify signs of pre-eclampsia and/or worsening blood pressure [PDF]

open access: yes, 2019
Background Hypertensive disorders of pregnancy complicate 10% of pregnancies and can have serious consequences. Aims To explore the experiences of pregnant women with a history of hypertension using an innovative home blood pressure monitoring ...
Kay, L., Khalil, A., Sheehan, E.
core   +2 more sources

Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy

open access: yesThe FEBS Journal, Volume 293, Issue 2, Page 325-347, January 2026.
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro   +2 more
wiley   +1 more source

Immune reconstitution inflammatory syndrome, human herpesvirus 8 viremia, and HIV-associated multicentric Castleman disease

open access: yesInternational Journal of Infectious Diseases, 2016
Kaposi's sarcoma and multicentric Castleman Disease are HIV-related disease processes that are associated with human herpesvirus 8 (HHV-8) infection.
Marc O. Siegel   +3 more
doaj   +1 more source

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