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Castleman Disease Pathogenesis

Hematology/Oncology Clinics of North America, 2018
Castleman disease (CD) describes a group of heterogeneous disorders with common lymph node histopathologic features, including atrophic or hyperplastic germinal centers, prominent follicular dendritic cells, hypervascularization, polyclonal lymphoproliferation, and/or polytypic plasmacytosis.
David C, Fajgenbaum, Dustin, Shilling
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Treatment of castleman’s disease

Current Treatment Options in Oncology, 2005
Castleman's disease (CD) was first described in 1954 and further defined in 1956 by Castleman. Since then much has been learned about the heterogeneity of this condition. Subsequently, three pathologic classifications have been developed (hyaline vascular variant, plasma cell variant, and mixed variant) and two clinical classifications (unicentric ...
Angela, Dispenzieri, Morie A, Gertz
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Castleman's disease in children

Journal of Pediatric Surgery, 1986
A three and one-half-year-old girl and a 12-year-old boy presented with features of the two clinical presentations of Castleman's disease or giant lymph node hyperplasia. The girl presented with anemia, fever, night sweats, hypergammaglobulinemia, and a palpable abdominal mass.
R W, Powell   +3 more
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Castleman's disease of the urachus

Urology, 2004
Castleman's disease (angiofollicular lymphoid hyperplasia) is a rare heterogeneous group of lymphoproliferative disorders of uncertain cause. Most cases occur as mediastinal masses, although extrathoracic involvement has been reported. Castleman's disease involving the genitourinary tract, one of the most infrequent organ systems affected, has so far ...
Udo, Rudloff   +4 more
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Castleman’s disease of the spleen

Acta Chirurgica Belgica, 2016
Castleman's disease (CD), also known as giant or angiofolicular lymphoid hyperplasia or lymphoid hamartoma, is a group of atypical lymphoproliferative disorders that share common lymph node histological features and may be localized either to a single lymph node (unicentric) or occur systemically (multicentric).Herein, we present a rare case of a of 75-
Dimitrios, Mantas   +4 more
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Castleman’s disease of the pleura

General Thoracic and Cardiovascular Surgery, 2011
Castleman's disease is a rare benign disease of the lymph nodes. Its origin from the pleura is rare. Surgical excision, when feasible, appears to provide good results. We encountered a patient who had the disease arising from the parietal pleura. We present the clinical scenario, investigations, and our management of the patient.
Rajaram, Burrah   +6 more
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Retroperitoneal Castleman's Disease

Urology, 2010
A 56-year-old postmenopausal woman with a history of colon cancer status after left hemicolectomy presented to our institution with abdominal pain, early satiety, and weight loss. Computerized tomography scan showed a large, enhancing, fat-containing mass displacing the left kidney posteriolaterally suspicious for a retroperitoneal liposarcoma.
A Ari, Hakimi   +3 more
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Castleman's disease.

Advances in clinical pathology : the official journal of Adriatic Society of Pathology, 1999
Castleman's disease (CD) is a rare atypical lymphoproliferative disorder whose morphology, soon after the original presentation of Castleman et al., has been definitely subdivided in a hyaline vascular (HV) and plasma cell (PC) histopathological pattern, with intermediate variants.
PALESTRO G   +3 more
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Castleman disease in pregnancy

Obstetrics & Gynecology, 1997
Castleman disease, a rare disorder characterized by benign proliferation of lymphoid tissues, generally presents as a solitary mediastinal mass. We report the first case of this disease during pregnancy.A 32-year-old woman presented with a large abdominal mass and vaginal bleeding during the second trimester of pregnancy.
Y, Abramov   +4 more
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Diagnosis of Castleman Disease

Hematology/Oncology Clinics of North America, 2018
Castleman disease (CD) is a rare and heterogenous group of disorders sharing in common an abnormal lymph node pathology. CD comprises distinct subtypes with different prognoses. Unicentric CD and multicentric CD are featured by specific systemic manifestations and may be associated with Kaposi sarcoma, non-Hodgkin and Hodgkin lymphoma, and POEMS ...
Raphaël, Szalat, Nikhil C, Munshi
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