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Right-sided cheek mass in a 10-year-old male
Otolaryngology Case Reports, 2021 Background: Castleman disease is a lymphoproliferative disorder that can present in multiple locations throughout the body. While considered a benign entity, Castleman disease in the pediatric head and neck can resemble other common childhood ...
John L. Wilson +3 more
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European Journal of Haematology, 2022 Treatment options for multicentric Castleman disease (MCD) remain limited. The only FDA‐approved drug is siltuximab for idiopathic MCD (iMCD), but the response rate with siltuximab is less than 50%.
M. Rehman +9 more
semanticscholar +1 more source
Annals of the Rheumatic Diseases, 2001 A 65 year old woman presented in February 1998 with joint pains, mild weight loss, and a low grade irregular fever. Initially, pain was localised around both shoulder joints. Subsequently, elbows, wrists, hips, and knees were affected, with morning stiffness, but without particular swelling. The symptoms were accentuated by movement, but also persisted
Riccio A +5 more
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Candidate biomarkers for idiopathic multicentric Castleman disease
Journal of Clinical and Experimental Hematopathology, 2022 The clinical manifestations of idiopathic multicentric Castleman disease (iMCD) are thought to be caused by an excess of inflammatory cytokines; however, the mechanism is yet to be known. In addition to IL-6, inflammatory cytokines, such as IL-1β and TNF-
R. Sumiyoshi, T. Koga, A. Kawakami
semanticscholar +1 more source
Blood Advances, 2020 Castleman disease (CD) includes a group of rare and heterogeneous disorders with characteristic lymph node histopathological abnormalities. CD can occur in a single lymph node station, which is referred to as unicentric CD (UCD).
F. Van Rhee +28 more
semanticscholar +1 more source
A Review of Genetic Abnormalities in Unicentric and Multicentric Castleman Disease
Biology, 2021 Simple Summary Castleman disease is a rare hematopoietic disorder with a broad spectrum of clinical presentations. Different subtypes have been described based on how many lymph nodes are involved, histologic appearance, and associated viral infections ...
Alexandra Butzmann +4 more
semanticscholar +1 more source
Castleman Disease Mimicking Ovarian Tumour
Gynecology Obstetrics & Reproductive Medicine, 2016 Castleman disease is a lymphoid disease characterized by herpes virus infection associated hyperplasia of lymphatic tissue. Castleman disease is generally localized in the mediastinum (70%) and the regions that it may be seen outside of the thorax are ...
Alper Karalök +7 more
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Multicentric Castleman's Disease [PDF]
Medical Journal Armed Forces India, 2002 Castleman's disease is a rare, atypical lymphoproliferative disorder that is morphologically and clinically heterogeneous and is associated with a risk of developing malignant lymphoma. It represents a distinct form of lymph node hyperplasia rather than a neoplasm or a hamartoma. In Castleman's original report, this lesion was described as solitary and
M K, Gupta, S K, Magu, A, Behl
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Journal of Cancer Research and Clinical Oncology, 2021 To explore the clinical features and immunological mechanisms of Castleman disease (CD) complicated with autoimmune diseases (AID). We explored the prevalence and clinical manifestations of CD complicated with AID by reviewing clinical, pathological, and
Dao-Ping Sun +9 more
semanticscholar +1 more source
Castleman disease: an uncommon diagnosis in pediatrics
Autopsy and Case Reports, 2012 First described by Dr. Benjamin Castleman in 1956, Castleman disease is an uncommon disease of an etiology that is not yet thoroughly known. Three distinct histological subtypes have already been described: hyaline-vascular-, plasma cell-, and human ...
Paula Martinez Vianna +6 more
doaj +1 more source