Results 191 to 200 of about 63,481 (261)

<i>In-vivo</i> antidiarrheal activity of aqueous and hydroethanolic extracts of <i>Anacardium occidentale</i> and <i>Khaya senegalensis</i> used in Benin (West Africa) in a castor oil-induced diarrhea model traditionally. [PDF]

Front Pharmacol
Hounsa E, Fagla SM, Agbodjento E, Klotoe JR, Dougnon VT.   +4 more
europepmc   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Sustainable Design of High-Performance Polyurethanes Using Medium-Chain-Length Polyhydroxyalkanoates. [PDF]

Polymers (Basel)
Nikodinovic-Runic J, Rao CV, Guzik M, Zimowska M, Milivojevic D, Ponjavic M.   +5 more
europepmc   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Unveiling the anti-diarrheal potential of <i>Persicaria vivipara</i>: phytochemical characterization and opioid receptor-targeted <i>in vivo</i> and <i>in silico</i> studies. [PDF]

RSC Adv
Farzeen I, M Al-Qaaneh A, Ishaq AR, Yasmeen M, Jaan Z, Ijaz MU, Abdel-Maksoud MA, Almutairi S, Alsabih AO, Aufy M, Ashraf A, El-Nashar HAS.   +11 more
europepmc   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Early Outcomes of a Curvature-Guided Strategy for Dual-Branch Revascularization in Zone 1 TEVAR. [PDF]

J Clin Med
Zhang L, Shu C, Li R, Xia D, Li X.
europepmc   +1 more source

Advances in 3D Bioprinting for Breast Cancer Modeling: Tumor Microenvironment, Metastasis, and Drug Screening

Advanced Healthcare Materials, EarlyView.
Three‐dimensional bioprinting transforms breast cancer modeling from simple constructs into spatially organized, multicellular, perfused, and patient‐derived platforms. This review shows how bioinks, cellular composition, architecture, and flow govern tumor behavior and drug response, while revealing why complexity alone is insufficient without ...
Mustafa Nakipoglu, Mahboobeh Mahmoodi, Ehsanul Hoque Apu, Fahimeh Shahabipour, Sibel Emir Diltemiz, Sanjib Saha, Halima Alem, Nureddin Ashammakhi   +7 more
wiley   +1 more source

Analysis of biosynthetic genes of phenolamides in <i>Ricinus communis</i> L. based on metabolomics and transcriptomes. [PDF]

Front Plant Sci
Li H, Zhang X, Huang S, Li S, Xu C, Zhan C, Luo Y.   +6 more
europepmc   +1 more source

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

Advanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão, Susana Simões, Paulo Rodrigues‐Santos, Vitor Francisco, Akhilesh Rai, Lino Ferreira   +5 more
wiley   +1 more source