Results 361 to 370 of about 219,417 (396)

Current Status of Sequential Treatment for Castration-resistant Prostate Cancer: A Retrospective Analysis. [PDF]

Cancer Diagn Progn
Oshinomi K, Mugita T, Inoue T, Omizu M, Yamagishi M, Nakagami Y, Nagata M, Shimoyama H, Ota M, Morita J, Sasaki H, Matsubara E, Saito K, Fuji K, Morita M, Fukagai T.   +15 more
europepmc   +1 more source

The Predictive Role of the Gleason Score in Determining Prognosis to Systematic Treatment in Metastatic Castration-Sensitive Prostate Cancer: A Systematic Review and Network Meta-Analysis. [PDF]

J Clin Med
Wu YC, Wang SI, Lu LY, Wu MY, Wu PL, Hsieh TY, Sung WW.   +6 more
europepmc   +1 more source

Juvenile nephropathy resembling human nephronophthisis–medullary cystic kidney disease in a 9‐month‐old domestic shorthaired cat

Journal of Small Animal Practice, EarlyView.
N. Goody, J. Poldy, A. Malbon, T. Morrison, I. Montanes‐Sancho, S. Dancer, D. Gunn Moore   +6 more
wiley   +1 more source

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Abiraterone and Olaparib for Metastatic Castration-Resistant Prostate Cancer.

NEJM Evidence, 2022
Abiraterone and Olaparib for Metastatic Prostate CancerPatients with metastatic castration-resistant prostate cancer, regardless of homologous recombination repair gene mutation status, received either abiraterone and olaparib or abiraterone and placebo ...
N. Clarke, A. Armstrong, A. Thiery-Vuillemin, M. Oya, N. Shore, E. Loredo, G. Procopio, J. de Menezes, G. Girotto, Ç. Arslan, N. Mehra, F. Parnis, E. Brown, F. Schlürmann, J. Joung, M. Sugimoto, J. Virizuela, U. Emmenegger, J. Navrátil, G. Buchschacher, C. Poehlein, E. Harrington, C. Desai, Jinyu Kang, F. Saad   +24 more
semanticscholar   +1 more source

To castrate or not to castrate? That is the question…

Veterinary Record, 2023
There is growing evidence that surgical castration of dogs may not bring all the benefits previously assumed. Times have changed too, and vets and clients are increasingly questioning whether routine castration should continue to be considered best practice.
openaire   +2 more sources

Castration

Journal of the American Psychoanalytic Association, 1991
Castration is not a metaphor within the array of psychoanalytic theories, but a pathological belief operative in the unconscious, which originated during the period of childhood sexuality. Of the two major anxieties, separation and castration, castration anxiety is the most overlooked in clinical discourse and theoretical awareness.
openaire   +2 more sources

Randomized, Double-Blind, Phase III Trial of Ipilimumab Versus Placebo in Asymptomatic or Minimally Symptomatic Patients With Metastatic Chemotherapy-Naive Castration-Resistant Prostate Cancer.

Journal of Clinical Oncology, 2017
Purpose Ipilimumab increases antitumor T-cell responses by binding to cytotoxic T-lymphocyte antigen 4. We evaluated treatment with ipilimumab in asymptomatic or minimally symptomatic patients with chemotherapy-naive metastatic castration-resistant ...
T. Beer, E. Kwon, C. Drake, K. Fizazi, C. Logothetis, G. Gravis, V. Ganju, J. Polikoff, F. Saad, Piotr Humanski, J. Piulats, P. González Mella, S. Ng, D. Jaeger, F. Parnis, F. Franke, J. Puente, Roman Carvajal, L. Sengeløv, M. McHenry, Arvind Varma, A. V. D. van den Eertwegh, W. Gerritsen   +22 more
semanticscholar   +1 more source

Self-castration

Irish Journal of Medical Science, 2001
Deliberate genital self-mutilation is rare. Successful self-castration has been reported in a small number of individuals.This study reports one such case of self-castration in a transsexual who was dissatisfied with waiting times for sex reassignment surgery (SRS).The apparent triggering factor in this case appears to be depression related to the ...
D. Murphy, R. Grainger, M. Murphy
openaire   +3 more sources

Castration in Germany

Annals of Sex Research, 1989
The medical and legal application of castration, including the forced castration of sexual offenders in Germany during the Nazi period from 1934 – 1945, is discussed in a cultural-historical introduction. A contemporary sample of 104 voluntary castrates (70% pedophiles, 25% aggressive sexual offenders, 3% exhibitionists, and 2% homosexuals) was ...
Reinhard Wille, Klaus M. Beier
openaire   +2 more sources

Enzalutamide Versus Bicalutamide in Castration-Resistant Prostate Cancer: The STRIVE Trial.

Journal of Clinical Oncology, 2016
PURPOSE Enzalutamide, a potent oral androgen receptor inhibitor, improves survival in men with metastatic castration-resistant prostate cancer (CRPC) before and after chemotherapy.
D. Penson, A. Armstrong, R. Concepcion, N. Agarwal, C. Olsson, L. Karsh, C. Dunshee, Fong Wang, Kenneth Wu, A. Krivoshik, D. Phung, C. Higano   +11 more
semanticscholar   +1 more source