Results 171 to 180 of about 637,030 (304)

Intramuscular administration of mesenchymal stromal cells in a cat with asthma: case report. [PDF]

J Vet Intern Med
Anderson de Oliveira P, Passos Maeda C, Barbalho Bianchi P, Baracho Trindade Hill JE, Baracho Trindade Hill A.   +4 more
europepmc   +1 more source

Designed Liquid Crystalline Nanoassemblies From Clinically Validated Polyunsaturated Lipids for Combined Antioxidant, Anti‐Apoptotic, and Neurotrophic Treatments

Advanced Healthcare Materials, EarlyView.
Ionizable lipid nanoparticles target multiple pathological pathways in neurodegeneration. The designed self‐assembled materials undergo a pH‐triggered structural transformation from a cubosome/hexosome coexistence to a hexosome phase, enhancing intracellular delivery of a multi‐target phytochemical formulation. The antioxidant‐loaded pH‐responsive LNPs
Thelma Akanchise, Fucen Luo, Borislav Angelov, Yuru Deng, Angelina Angelova   +4 more
wiley   +1 more source

Interaction of <i>Plasmodium yoelii</i> tryptophan-rich antigen 7 with CD71 on macrophage membrane regulates host inflammatory response. [PDF]

iScience
Sun Y, Chen Z, Du C, Lei Y, Li J, Zhang H, Huang X, Wang B, Zuo S, Lv Z, Cao J, Han S, Cheng Y.   +12 more
europepmc   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Integrating design-of-experiments (DOE) optimization and risk assessment towards a safe and simplified electroporation protocol for Toxoplasma gondii. [PDF]

PLoS Negl Trop Dis
Srivastava PN, Perewernycky N, Filippo L, Lefsrud LM, Ungrin M.   +4 more
europepmc   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Atopic march protocol involving sequential skin and lung inflammation elicited by epicutaneous Staphylococcus aureus and allergen exposure. [PDF]

STAR Protoc
Kline SN, Feller LE, Wills D, Damarla R, Archer NK.   +4 more
europepmc   +1 more source

Examination of Human Skeletal Remains and Artifacts from el-Qantir, Egypt [PDF]

, 2011
Stephen, Emily
core   +1 more source

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

DCPS modulates TDP-43-linked neurodegeneration through P-body-mediated RNA decay. [PDF]

Neuron
Ye Y, Zhang Z, Xiao Y, Zhu C, Wright N, Asbury J, Huang Y, Wang W, Gomez-Isaza L, Troncoso JC, He C, Sun S.   +11 more
europepmc   +1 more source