Results 271 to 280 of about 636,485 (333)

The sphingolipid metabolite sphingosine protects against hypertension by targeting metabolic-inflammatory crosstalk via the NLRP3 inflammasome. [PDF]

Int J Cardiol Cardiovasc Risk Prev
Li W, Zhou D, Ji Y, Yang M, Yang Y, Dao M, He X, Jin X.   +7 more
europepmc   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Brucella abortus infection exploits ZDHHC3-mediated STAT3 palmitoylation to regulate host responses and promote persistence. [PDF]

Vet Res
Liu X, Yu J, Chen Y, Liu H, Liu N, Peng Q.   +5 more
europepmc   +1 more source

Hybrid Scaffolds Decouple Biochemical & Biophysical Regulation of Cell Phenotype

Advanced Healthcare Materials, EarlyView.
Replicating tissue‐specific extracellular matrix is crucial for understanding its role in disease. This work demonstrates independent control over stiffness, composition and 3D collagen architecture using hybrid scaffolds: patterned collagen perfused with defined hydrogels.
Xinyuan Song, Samantha C. Mitchell, Abbie N. Smart, William Hardiman, Daniel V. Bax, Ceri E. Staley, Catherine Probert, Pamela Collier, Marian Meakin, Alison A. Ritchie, Tania Mendonca, Amanda J. Wright, Victoria James, Anna M. Grabowska, Catherine L. R. Merry, Serena M. Best, Ruth E. Cameron, Jennifer C. Ashworth   +17 more
wiley   +1 more source

Serum osteopontin as a prognostic biomarker in acute exacerbations of chronic obstructive pulmonary disease. [PDF]

Front Immunol
Ma KS, Li LN, Ma YC, Fan RL, Chen G, Zhao H, Qu KX, Fu L.   +7 more
europepmc   +1 more source

Overview of patients by showing the participating study cats with feline infectious peritonitis (FIP), including signalment, number of additional cats in the household, corresponding healthy partner cats (Kp cats), method of diagnosis of feline infectious peritonitis (FIP), FIP-associated signs, Xraphconn® treatment dose, other diseases at the start of and developing during treatment, adverse effects, and additional symptomatic therapy (table adapted from [31,42]).

Katharina Zwicklbauer (16803577), Pilar Grassl (22238221), Martin Alberer (16803586), Laura Kolberg (16803589), Nina A. Schweintzger (9153614), Sonja Härtle (3874582), Kaspar Matiasek (247011), Regina Hofmann-Lehmann (374215), Katrin Hartmann (295787), Caroline C. Friedel (7812728), Ulrich von Both (5799164)   +10 more
openalex   +1 more source

From Helping to Hoarding to Hurting: When the Acts of Good Samaritans Become Felony Animal Cruelty [PDF]

, 2011
Avery, Lisa
core   +2 more sources

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

Advanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu, Yiben Ouyang, Bo Wang, Xiaochun Zhang, Yanjun Guan, Ruichao He, Yuhui Cui, Junli Wang, Qianru Yao, Yixiao Tan, Xiwei Peng, Xing Xiong, Sice Wang, Dongdong Li, Haofeng Cheng, Tianqi Su, Xiaoyang Fu, Jinjuan Zhao, Mingqian Yu, Yi Wang, Jiang Peng, Yu Wang   +21 more
wiley   +1 more source

Protocol to assess myogenic effects of 3T3-L1 and primary murine fibro-adipogenic progenitors on C2C12 myoblast differentiation. [PDF]

STAR Protoc
Norris AM, Appu AB, Kopinke D.
europepmc   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source