Results 41 to 50 of about 126,840 (295)

sj-docx-1-cat-10.1177_10760296231184216 - Supplemental material for Risk of Bleeding Associated With Outpatient Use of Rivaroxaban in VTE Management at a National Referral Hospital in Western Kenya

, 2023
Supplemental material, sj-docx-1-cat-10.1177_10760296231184216 for Risk of Bleeding Associated With Outpatient Use of Rivaroxaban in VTE Management at a National Referral Hospital in Western Kenya by Dennis Njuguna, BPharm, Francis Nwaneri, MD, Allyson C.
Samuel Nyanje (16551147), Allyson C. Prichard (16551144), Dennis Njuguna (16551138), Imran Manji (3471221), Naftali Busakhala (822699), Francis Nwaneri (16551141), Gabriel Kigen (355638), Sonak D. Pastakia (9460440), Emily O’Neil (16551150)   +8 more
core   +1 more source

The Implications of Policies on the Welfare of Free-Roaming Cats in New Zealand

Animals, 2022
A lack of national legislation for cat management in New Zealand poses challenges for ensuring that practices are consistently humane and effective. In this paper, we review the current cat management policies in New Zealand and the implications they ...
Christine L. Sumner, Jessica K. Walker, Arnja R. Dale   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Influences of roaming domestic cats on wildlife activity in patchy urban environments

Frontiers in Ecology and Evolution, 2023
Roaming domestic cats (Felis catus) are recognised as a threat to wildlife globally. Yet management of pet cats in urbanised areas is not regularly mandated, and management of feral cats in urbanised areas is rarely implemented.
Loren L. Fardell, Loren L. Fardell, Chris R. Pavey, Christopher R. Dickman   +3 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Cat–Owner Relationship and Cat Behaviour: Effects of the COVID-19 Confinement and Implications for Feline Management [PDF]

, 2022
SIMPLE SUMMARY: The aim of this study was to explore the effects of the Italian COVID-19 lockdown on the cat-owner relationship and on cat behaviour. In order to do so, we used a questionnaire to obtain information on the owner and cat’s demographics ...
Mariti, C, Bowen, Jonathan E., Fatjó i Ríos, Jaume, Federica Pirrone, Grondona, A, Bowen, JE, Gazzano, Angelo, Borrelli, C, Francesco P. Di Iacovo, Fatjo, J, Pirrone, Federica, Di Iacovo, Francesco P., Angelo Gazzano, Bowen, Jonathan, Piotti, P, Di Iacovo, FP, Mota-Rojas, D, Fatjó, Jaume, Piotti, Patrizia, Grondona, Anna, Daniel Mota-Rojas, Mota-Rojas, Daniel, Carmen Borrelli, Anna Grondona, Chiara Mariti, Riggio, G, Borrelli, Carmen, Pirrone, F, Riggio, Giacomo, Mariti, Chiara, Patrizia Piotti, Jaume Fatjó, Jonathan E. Bowen, Giacomo Riggio, Gazzano, A   +34 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Socialising kitties: A quantitative survey of US cat owner attitudes towards kitten and adult cat socialisation programmes

Animal Welfare
Socialisation is important for normal social and behavioural development in companion animals. However, little research has focused on kitten socialisation or owner attitudes towards kitten socialisation programmes.
Jennifer K Link, Carly M Moody
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source