Results 181 to 190 of about 51,862 (294)

Sphingosine‐1‐Phosphate Receptor 1 Promotes Ovarian Cancer Tumorsphere Proliferation and Metastasis

open access: yesInternational Journal of Cancer, EarlyView.
In high‐grade serous ovarian cancer, malignant ascites frequently arise as ovarian cancer cells shed from the primary tumor and aggregate into tumorspheres, severely limiting treatment success. To date, little is known about the mechanisms governing tumorsphere endurance and metastasis within the ascites once formed.
Núria Gendrau‐Sanclemente   +12 more
wiley   +1 more source

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

open access: yesInternational Journal of Cancer, EarlyView.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim   +22 more
wiley   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

open access: yesiNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu   +5 more
wiley   +1 more source

Digital and tomographic identification of risk indicators for gingival recession in the mandibular anterior region: A cross‐sectional study

open access: yesJournal of Periodontology, EarlyView.
Abstract Background To assess clinical and anatomical risk indicators for mid‐buccal gingival recessions (GRs) in the mandibular anterior region using digital and tomographic tools. Methods A cross‐sectional study was conducted on 103 patients (618 teeth).
Gonzalo Blasi   +5 more
wiley   +1 more source

Hospital Volume and Post‐Hepatectomy Liver Failure After Major Hepatectomy

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background Post‐hepatectomy liver failure (PHLF) following major hepatectomy (MH) increases the risk of morbidity and death. The relationship between institutional MH volume, PHLF, and outcomes is not well characterized. Methods Adults undergoing MH from 2014 to 2021 in the ACS NSQIP hepatectomy‐targeted database were included.
Xane D. Peters   +8 more
wiley   +1 more source

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