Results 271 to 280 of about 50,434 (331)

Snow Leopards: What's Next? 雪豹:何去何从?

open access: yesIntegrative Conservation, EarlyView.
In 2003–2023, the number of papers on snow leopards has grown by a 20‐fold increase, especially concerning ecology and conservation. However, important knowledge gaps persist, and this commentary identifies the major areas requiring advanced and focused investigations.
Sandro Lovari, Francesco Ferretti
wiley   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

open access: yesInterdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li   +9 more
wiley   +1 more source

Clinical Evaluation of Drug–Drug Interactions Between Bictegravir and Strong Inhibitors/Inducers of the CYP3A4, UGT1A1, or P‐gp Pathways

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract In addition to antiretroviral therapy (ART), people with HIV often take medications to treat comorbidities. It is therefore important to assess these medications for potential drug‐drug interactions, which may affect the safety and efficacy of ART. Three phase I studies were conducted in adult participants without HIV. The pharmacokinetics (PK)
Priyanka Arora   +4 more
wiley   +1 more source

Gel Containing Catechin and Mesoporous Silica Nanoparticles for Protecting Root Dentin Against Erosion: An In Situ Study

open access: yesMicroscopy Research and Technique, EarlyView.
Gels containing EGCG adsorbed on mesoporous silica nanoparticles have a protective effect against dentin erosion. ABSTRACT This study evaluated the in situ anti‐erosive effect of gels containing epigallocatechin‐3‐gallate (EGCG) isolated and adsorbed on mesoporous silica nanoparticles (EGCG/MSN) on eroded dentin.
Helaine Cajado Alves   +5 more
wiley   +1 more source

Major Ozonated Autoheamotherapy Alleviates Skeletal Muscle Ischemia/Reperfusion Injury by Regulating Nrf2/HO‐1 Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Skeletal muscle ischaemia/reperfusion (I/R) injury remains a clinically significant condition characterized by muscular dystrophy. Although ozone therapy has shown protective potential against I/R injury in animal models of various organs including skeletal muscle, its precise mechanistic underpinnings require further elucidation.
Hui‐Zhuang Guo   +2 more
wiley   +1 more source

The Longitudinal Impact of Radiotherapy on Osseointegrated Hearing Aid Outcomes and Complications

open access: yesThe Laryngoscope, EarlyView.
Radiation significantly increases the risk of both abutment and implant‐related osseointegrated hearing aid complications, particularly in the long term. Cumulative incidence plots demonstrate a greater discrepancy in complication rates between groups as time increases. Ongoing surveillance for complications in this population is critical.
Benjamin D. Lovin   +8 more
wiley   +1 more source

Effects of a high‐fat diet on gut microbiota and possible implications for bone health in male Wistar rats

open access: yesLipids, EarlyView.
Abstract Diet plays an important role in the composition of gut microbiota. Emerging research suggests that bone homeostasis can also be influenced by the gut microbiota. The aim of this study was to assess possible alterations in gut microbiota in an experimental obesity model induced by a high‐fat diet (HFD) and the possible effects on parameters of ...
Fernanda Guedes Rodrigues   +6 more
wiley   +1 more source

Isolation of Candida norvegensis from Clinical Specimens: Four Case Reports [PDF]

open access: yes, 2017
Altwegg, Martin   +3 more
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