Results 211 to 220 of about 265,603 (330)

Polyamine-mediated crosstalk in plant-microbe systems: implications for stress tolerance and crop protection. [PDF]

Front Plant Sci
Rezaee Danesh Y, La Bella E, Cannata C, Vitale A.   +3 more
europepmc   +1 more source

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

Two distinct alcohol dehydrogenase classes mediate bacterial 2-hydroxyethylphosphonate catabolism. [PDF]

Protein Sci
Piazza F, Rodella M, Salanti N, Merici G, Rossi E, Rivetti C, Götzinger F, Pallitsch K, Peracchi A.   +8 more
europepmc   +1 more source

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

Advanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma, Zhen Zhao, Chuan Guo, Yuheng Liu, Yu Wang, Dengbo Yao, Weiqiang Lan, Dejun Zhong, Chen Fan, Yao He, Mei Zhang, Qingquan Kong, Yunfeng Lin   +12 more
wiley   +1 more source

ACAD8-mediated valine catabolism inhibits mTOR signaling to suppress lipid accumulation and progression of clear cell renal cell carcinoma. [PDF]

Transl Oncol
Fan R, Dong Z, Wu W, Jia Y, Tan H, Wang Q, Zhang X.   +6 more
europepmc   +1 more source

Context‐Dependent Inverse Association of Glucose–Lipid Metabolic Status With Anemia: Evidence From Multinational Multicohort Analyses

Advanced Science, EarlyView.
Across six multinational cohorts, higher triglyceride–glucose index values are consistently associated with lower prevalent and incident anemia, despite their established adverse cardiometabolic significance. This inverse relationship varies across inflammatory, cardiovascular, and renal contexts, suggesting that glucose–lipid metabolic status carries ...
Guosong Jiang, Xinxing Wang, Lianfeng Xie, Wenna Ding, Yingyong Yin, Mei Yao, Zhibo Cui, Kaiqiang Tang, Lijie Zhong, Zhi Wang, Jia Wang, Lei Lei, Xiaoxiao Qu, Chi‐E. Qiu   +13 more
wiley   +1 more source

Postharvest senescence of green vegetables and the role of glutathione metabolism: current state of knowledge and future research opportunities. [PDF]

Front Plant Sci
Bozzo GG, Sivakumar D, Yan Y, Beltrán Plascencia A.   +3 more
europepmc   +1 more source

Single‐Nucleus Transcriptomic Atlas of Human Vellus Hair Pilosebaceous Units Reveals Age‐Associated Remodeling

Advanced Science, EarlyView.
Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li, Zhuoqiong Qiu, Xiaoyu Pan, Geyang Xu, Shanshan Peng, Ronghui Zhu, Qiuyang Luo, Xiaokai Fang, Xu Yao, Wei Li   +9 more
wiley   +1 more source

Human brown fat metabolism associates with systemic branched-chain amino acids homeostasis. [PDF]

Mol Metab
U-Din M, Acosta FM, Saari T, de Mello Laaksonen VD, van der Kolk BW, Monfort-Pires M, Clemente-Postigo M, Niemi T, Taittonen M, Tuomainen M, Fromme T, Lehtonen M, Kristiansen K, Newman JW, Pietiläinen KH, Pihlajamäki J, Pirinen E, Klingenspor M, Hanhineva K, Raiko J, Virtanen KA.   +20 more
europepmc   +1 more source

Age‐Dependent Prognostic Significance of Preoperative Transthyretin After Curative Resection for Stage I–III Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Preoperative malnutrition and systemic inflammation are established determinants of adverse outcomes in colorectal cancer (CRC). Transthyretin (TTR), a rapid‐turnover hepatic protein, reflects both nutritional and inflammatory status; however, its clinical utility may be influenced by age‐ and sex‐related variability.
Ayane Kawata, Yuji Miyamoto, Hiro Nakamura, Takahiko Akiyama, Kota Arima, Katsuhiro Ogawa, Yukiharu Hiyoshi, Masaaki Iwatsuki   +7 more
wiley   +1 more source