Results 41 to 50 of about 125,187 (158)

Isolation and Characterization of Random Citrate Synthase Variants That Increase Acetate Generation by Escherichia coli

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT A method to select Escherichia coli citrate synthase variants having reduced activity was developed based initially on the increased generation of acid, observed visually by prolonged color change in the pH indicator bromocresol purple. Five hundred fifty‐two potential variants were isolated and each were cultured on glucose as sole carbon ...
Jeffrey K. Dodelin   +3 more
wiley   +1 more source

Scaffolding a Low‐Cost Experiential Bioreactor Module: Reducing Cognitive Load to Enhance Competency and Self‐Efficacy

open access: yesBiochemistry and Molecular Biology Education, EarlyView.
ABSTRACT Low‐cost experiential modules are critical for democratizing biotechnology education, yet most undergraduates lack hands‐on experience with continuous‐culture bioreactor operations, which are fundamental to industrial bioprocessing. This study employed design‐based research across two iterative cycles (Fall 2024, n = 8; Fall 2025, n = 11) to ...
Russell K. Pirlo   +2 more
wiley   +1 more source

Yeast carbon catabolite repression [PDF]

open access: yes, 1998
28 pages, 5 figures, 2 tables.Glucose and related sugars repress the transcription of genes encoding enzymes required for the utilization of alternative carbon sources; some of these genes are also repressed by other sugars such as galactose, and the ...
Gancedo, Juana M.
core  

Monitoring and Mitigation Strategies for Hazardous Compounds in Chinese Rice Wine (Huangjiu): A Comprehensive Review

open access: yesFood Safety and Health, EarlyView.
This review elucidates the formation pathways and detection technologies for ethyl carbamate, biogenic amines, and higher alcohols in Huangjiu. It concludes that integrated control frameworks are essential to decouple safety risks from the metabolic processes responsible for flavor development.
Lulu Liu   +5 more
wiley   +1 more source

Glucose-mediated catabolite repression in Sinorhizobium meliloti [PDF]

open access: yes, 2017
: Alfalfa plants and the bacteria Sinorhizobium meliloti interact in a symbiotic relationship in which the alfalfa plant receives a usable form of nitrogen, ammonia, to use as a fertilizer, while the bacteria receive a carbon and energy source from the ...
Murnin, Emily R
core  

Simultaneous carbon catabolite repression governs sugar and aromatic co-utilization in Pseudomonas putida M2 [PDF]

open access: yes, 2023
Pseudomonas putida have emerged as promising biocatalysts for the conversion of sugars and aromatics obtained from lignocellulosic biomass. Understanding the role of carbon catabolite repression (CCR) in these strains is critical to optimize biomass ...
Awasthi, Deepika   +7 more
core   +1 more source

Ion binding sites and intermediate domain closure induced by D‐serine in the GluD1 ligand‐binding domain

open access: yesThe FEBS Journal, EarlyView.
GluD1 belongs to the ionotropic glutamate receptors and has important functions in the brain and brain diseases. We report the crystal structure of the GluD1 ligand‐binding domain with D‐serine and zinc ions. MD simulations supported promiscuous binding of cations and that chloride ions play a stabilizing role. Pro725 seems to hinder interlobe closure,
Flemming Steen Jørgensen   +4 more
wiley   +1 more source

Fructose Mediated Catabolite Repression in Sinorhizobium meliloti [PDF]

open access: yes, 2015
Plants are unable to utilize the N2 form found in the soil environment. Bacteria known as rhizobia are capable of fixing this nitrogen into a form useable by the plant and initiate a symbiotic relationship in the legume root.
Timmerman, Clinton
core  

Different levels of catabolite repression optimize growth in stable and variable environments.

open access: yesPLoS Biology, 2014
Organisms respond to environmental changes by adapting the expression of key genes. However, such transcriptional reprogramming requires time and energy, and may also leave the organism ill-adapted when the original environment returns.
Aaron M New   +7 more
doaj   +1 more source

Solid‐State Fermentation of Legumes: Multi‐Scale Structural Modifications to Unlock Techno‐Functional Properties

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT Legumes are increasingly used as functional ingredients in plant‐based foods. However, their compact endogenous structure restricts techno‐functional properties. Conventional fractionation methods that isolate proteins further impair these properties and generate co‐products.
Deepak Subramani   +5 more
wiley   +1 more source

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