Results 71 to 80 of about 125,187 (158)

Reimagining Lignin Valorization: Synthetic Biology–Enabled Sustainable Aromatic Carbon Biomanufacturing

Advanced Science, Volume 13, Issue 47, 24 August 2026.
The diagram illustrates a sustainable model of lignin valorization and carbon cycling based on microbial cell factories. Using lignin as the feedstock, synthetic biology technologies, including depolymerization, cell factory construction, pathway gene module integration, and metabolic network regulation, are applied to convert lignin into bulk ...
Na Li, Jun‐Jie Zhangyang, Bing‐Zhi Li, Zhi‐Hua Liu, Ying‐Jin Yuan   +4 more
wiley   +1 more source

Lack of Differences in the Pharmacokinetics of Therapeutic Monoclonal Antibodies Between Japanese and Non‐Japanese Individuals

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta, Ashish Sharma, Bernd Meibohm   +2 more
wiley   +1 more source

Nature of the Effector of Catabolite Repression of ,B-Galactosidase in Escherichia coli [PDF]

, 2020
LOOMIS, WILLIAM F., JR. (Massachusetts Institute of Technology, Cambridge, Mass.), AND BORIS MAGASANIK. Nature of the effector of catabolite repression of f-galactosidase in Escherichia coli. J. Bacteriol. 92:170-177. 1966.-Many carbon sources were found

core  

Influence of Catabolite Repression and Inducer Exclusion on the Bistable Behavior of the lac Operon [PDF]

, 2004
A mathematical model of the lac operon which includes all of the known regulatory mechanisms, including external-glucose-dependent catabolite repression and inducer exclusion, as well as the time delays inherent to transcription and translation, is ...
Santillán, Moisés, Mackey, Michael C.
core   +1 more source

Rewiring a methanol-responsive regulatory system improves glucose–methanol co-utilization in Eubacterium limosum

Journal of Biological Engineering
Background Methanol is a promising one-carbon (C1) feedstock for sustainable bioproduction, and its mixotrophic co-utilization with other substrates can improve product formation.
Jiyun Bae, Hyunwoo Jung, Seulgi Kang, Chanho Park, Donghwi Lee, Sangrak Jin, Byung-Kwan Cho   +6 more
doaj   +1 more source

A Co-Fermentation Strategy from Corncob Hydrolysate to Enhance Simultaneous Co-Production of Lactic Acid and Ethanol

Fermentation
Efficient co-utilization of mixed sugars from lignocellulosic hydrolysates is often hindered by carbon catabolite repression and pretreatment-derived inhibitors. In this study, a co-fermentation strategy using Saccharomyces cerevisiae (S. cerevisiae) and
Xiaona Wang, Yongsheng Li, Yuanchun Zhang, Yuanyuan Ren, Hongzhi Ma, Jianguo Liu, Qunhui Wang   +6 more
doaj   +1 more source

Carbon Catabolite Repression Regulates the Production of the Unique Volatile Sodorifen of Serratia plymuthica 4Rx13

Frontiers in Microbiology, 2017
Microorganisms are capable of synthesizing a plethora of secondary metabolites including the long-overlooked volatile organic compounds. Little knowledge has been accumulated regarding the regulation of the biosynthesis of such mVOCs. The emission of the
Nancy Magnus, Teresa Weise, Birgit Piechulla   +2 more
doaj   +1 more source

Enhanced Natamycin production by Streptomyces natalensis in shake-flasks and stirred tank bioreactor under batch and fed-batch conditions

BMC Biotechnology, 2019
Background Natamycin is an antifungal polyene macrolide antibiotic with wide applications in health and food industries. Currently, it is the only antifungal food additive with the GRAS status (Generally Regarded as Safe).
Elsayed Ahmed Elsayed, Mohamed A. Farid, Hesham A. El-Enshasy   +2 more
doaj   +1 more source

Membrane Association and Catabolite Repression of the Sulfolobus solfataricus α-Amylase

Microorganisms, 2015
Sulfolobus solfataricus is a thermoacidophilic member of the archaea whose envelope consists of an ether-linked lipid monolayer surrounded by a protein S-layer.
Edith Soo, Deepak Rudrappa, Paul Blum
doaj   +1 more source

Catabolite repression and induction of the Mg2+-citrate transporter CitM of Bacillus subtilis [PDF]

, 2000
In Bacillus subtilis the citM gene encodes the Mg2+-citrate transporter. A target site for carbon catabolite repression (cre site) is located upstream of citM.
Konings, WN, Warner, JB, Warner, Jessica B., Magni, C, Krom, BP, Lolkema, JS   +5 more
core   +4 more sources