Results 71 to 80 of about 14,145 (207)

High‐Yield Production and Cost‐Effective Purification of an Alkali‐Resistant Hexameric Protein A Variant for Antibody Affinity Chromatography

open access: yesBiotechnology Journal, Volume 21, Issue 6, June 2026.
Graphical Abstract and Lay Summary We present a scalable method for producing the antibody‐binding ligand Z6AlkC, a six‐repeat, alkali‐resistant Protein A–derived Z domain with a terminal cysteine. The ligand was produced at high yield via extracellular secretion in bioreactors and subsequently purified by high‐productivity ultradiafiltration with low ...
Carolina Mota Natal   +11 more
wiley   +1 more source

catabolite repression

open access: yes, 2014
Citation: 'catabolite repression' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.C00871 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Selection of Trichoderma mutants with enhanced cellulase production and resistant to catabolite repression

open access: yes浙江大学学报. 农业与生命科学版, 2004
Due to high cost and relatively low efficiency of cellulase enzymes used for the saccharification of pretreated lignocelluloses, the improvement of cellulase secreting microorganisms is of vital importance.
Szakacs G, Megyeri L, Kovacs K, Zacchi G
doaj   +1 more source

Advancing Malic Acid Production of Aspergillus oryzae: Combined Process Optimization and Application of Various Substrates

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 6, Page 1634-1647, June 2026.
ABSTRACT In light of climate change and growing resource scarcity, microbial production of organic acids offers a sustainable alternative to fossil‐based chemical synthesis. In this study, malic acid production by Aspergillus oryzae was optimized through cultivation temperature adjustment and biotin supplementation, while organic acid formation from ...
Lukas Hartmann   +6 more
wiley   +1 more source

Investigation of carbon catabolite repression in Clostridium beijerinckii NCIMB 8052

open access: yes, 2001
Summary in English.Includes bibliographical references.The substrate basis for the industrial acetone-butanol-ethanol (ABE) fermentations, has been agricultural products rich in starch or sucrose, and employed taxonomically distinct amylolytic and ...
Rafudeen, M S
core  

A Co-Fermentation Strategy from Corncob Hydrolysate to Enhance Simultaneous Co-Production of Lactic Acid and Ethanol

open access: yesFermentation
Efficient co-utilization of mixed sugars from lignocellulosic hydrolysates is often hindered by carbon catabolite repression and pretreatment-derived inhibitors. In this study, a co-fermentation strategy using Saccharomyces cerevisiae (S. cerevisiae) and
Xiaona Wang   +6 more
doaj   +1 more source

Establishment of a Single‐Cell Minimal Medium: A Case Study for Microfluidic Cultivation of Corynebacterium glutamicum

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 6, Page 1648-1660, June 2026.
Conventional bulk media are often unsuitable for single‐cell cultivation and analysis because they provide excess nutrients or lack essential components. Redesigning the medium allows for controlled, defined growth, enabling the development of a robust minimal medium that supports quantitative and reproducible single‐cell analysis across different ...
Judith Wegmann   +5 more
wiley   +1 more source

Carbon Catabolite Repression Regulates the Production of the Unique Volatile Sodorifen of Serratia plymuthica 4Rx13

open access: yesFrontiers in Microbiology, 2017
Microorganisms are capable of synthesizing a plethora of secondary metabolites including the long-overlooked volatile organic compounds. Little knowledge has been accumulated regarding the regulation of the biosynthesis of such mVOCs. The emission of the
Nancy Magnus   +2 more
doaj   +1 more source

Salt Stress Induces Imbalanced ADI Pathway Gene Expressions in Pediococcus acidilactici Drives Citrulline Accumulation as an Ethyl Carbamate Precursor in Soy Sauce

open access: yesFood Bioengineering, Volume 5, Issue 2, Page 171-181, June 2026.
ABSTRACT Citrulline is the main precursor of a carcinogen compound ethyl carbamate (EC) in soy sauce. Accumulation of citrulline is mainly related to metabolism of arginine by Pediococcus acidilactici via the arginine deiminase (ADI) pathway during soy sauce fermentation.
Xiaodie Chen   +3 more
wiley   +1 more source

Influence of Catabolite Repression and Inducer Exclusion on the Bistable Behavior of the lac Operon

open access: yes, 2004
A mathematical model of the lac operon which includes all of the known regulatory mechanisms, including external-glucose-dependent catabolite repression and inducer exclusion, as well as the time delays inherent to transcription and translation, is ...
Santillán, Moisés, Mackey, Michael C.
core   +1 more source

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