Results 131 to 140 of about 142,847 (376)

Modifying factors of PD‐L1 expression on tumor cells in advanced non‐small‐cell lung cancer

open access: yesThoracic Cancer, Volume 13, Issue 23, Page 3362-3373, December 2022., 2022
Programmed death ligand‐1 (PD‐L1) is an essential biomarker guiding treatment in nononcogene addicted advanced lung adenocarcinoma, and many factors may impact its reproducibility and performance. This study demonstrated an increased probability of identifying PD‐L1‐positive samples in poorly differentiated, solid predominant, and EGFR wild‐type tumors.
Alejandro Avilés‐Salas   +11 more
wiley   +1 more source

The Super Patalan Numbers [PDF]

open access: yesJ. Integer Seq. 18 (2015), Article 15.3.3, 2014
We introduce the super Patalan numbers, a generalization of the super Catalan numbers in the sense of Gessel, and prove a number of properties analagous to those of the super Catalan numbers. The super Patalan numbers generalize the super Catalan numbers similarly to how the Patalan numbers generalize the Catalan numbers.
arxiv  

Immune Checkpoint Inhibitors and Cardiovascular Adverse Events

open access: yesESC Heart Failure, EarlyView.
Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna   +4 more
wiley   +1 more source

Cysteine restriction‐specific effects of sulfur amino acid restriction on lipid metabolism

open access: yesAging Cell, Volume 21, Issue 12, December 2022., 2022
The proposed mechanism of CR‐specific effects of SAAR on adipose metabolism. (1) Due to the lack of Cys in SAAR diets, it imposes both MR and CR. CR specifically results in decreased biosynthesis of the tripeptide glutathione. (2) Lower hepatic glutathione increases the abundance of the transcription factor Nrf2, which translocates to the nucleus and ...
Sailendra N. Nichenametla   +17 more
wiley   +1 more source

On the (n,k)-th Catalan numbers [PDF]

open access: yesCommun. Korean Math. Soc. 23(3) (2008) 349-356, 2015
In this paper, we generalize the Catalan number to the $(n,k)$-th Catalan numbers and find a combinatorial description that the $(n,k)$-th Catalan numbers is equal to the number of partitions of $n(k-1)+2$ polygon by $(k+1)$-gon where all vertices of all $(k+1)$-gons lie on the vertices of $n(k-1)+2$ polygon.
arxiv  

Hawking from Catalan

open access: yesJournal of High Energy Physics, 2016
19+8 pages, 5 ...
Jared Kaplan   +5 more
openaire   +3 more sources

Advanced Stage Head and Neck Cancer Diagnosis: HEADSpAcE Consortium Health Systems Benchmarking Survey

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Globally, most people with head and neck cancers (HNCs) are diagnosed with advanced‐stage disease. HNC diagnostic stage has multifactorial explanations, with the role of health system factors not yet fully investigated. Methods HNC centres (n = 18) from the HEADSpAcE Consortium were surveyed via a bespoke health system questionnaire
Grant Creaney   +201 more
wiley   +1 more source

Random graphs induced by Catalan pairs [PDF]

open access: yesarXiv, 2019
We consider Catalan-pair graphs, a family of graphs that can be viewed as representing certain interactions between pairs of objects which are enumerated by the Catalan numbers. In this paper we study random Catalan-pair graphs and deduce various properties of these random graphs.
arxiv  

Compliance with indoor and outdoor smoke-free ban in Catalan hospitals: what do patients think?

open access: yesTobacco Induced Diseases, 2018
Background In Catalan hospitals, compliance with smoke-free regulation has been evaluated by direct (air markers of tobacco consumption) and indirect methods (surveys to healthcare workers); however, patients have never been asked about their insight on ...
Laura Antón   +5 more
doaj   +1 more source

The Stochastic Entanglement and Phantom Motor Execution Hypotheses: A Theoretical Framework for the Origin and Treatment of Phantom Limb Pain

open access: yesFrontiers in Neurology, 2018
Phantom limb pain (PLP) is a debilitating condition common after amputation that can considerably hinder patients' quality of life. Several treatments have reported promising results in alleviating PLP. However, clinical evaluations are usually performed
Max Ortiz-Catalan, Max Ortiz-Catalan
doaj   +1 more source

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