Results 131 to 140 of about 142,847 (376)
Modifying factors of PD‐L1 expression on tumor cells in advanced non‐small‐cell lung cancer
Programmed death ligand‐1 (PD‐L1) is an essential biomarker guiding treatment in nononcogene addicted advanced lung adenocarcinoma, and many factors may impact its reproducibility and performance. This study demonstrated an increased probability of identifying PD‐L1‐positive samples in poorly differentiated, solid predominant, and EGFR wild‐type tumors.
Alejandro Avilés‐Salas+11 more
wiley +1 more source
The Super Patalan Numbers [PDF]
We introduce the super Patalan numbers, a generalization of the super Catalan numbers in the sense of Gessel, and prove a number of properties analagous to those of the super Catalan numbers. The super Patalan numbers generalize the super Catalan numbers similarly to how the Patalan numbers generalize the Catalan numbers.
arxiv
Immune Checkpoint Inhibitors and Cardiovascular Adverse Events
Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna+4 more
wiley +1 more source
Cysteine restriction‐specific effects of sulfur amino acid restriction on lipid metabolism
The proposed mechanism of CR‐specific effects of SAAR on adipose metabolism. (1) Due to the lack of Cys in SAAR diets, it imposes both MR and CR. CR specifically results in decreased biosynthesis of the tripeptide glutathione. (2) Lower hepatic glutathione increases the abundance of the transcription factor Nrf2, which translocates to the nucleus and ...
Sailendra N. Nichenametla+17 more
wiley +1 more source
On the (n,k)-th Catalan numbers [PDF]
In this paper, we generalize the Catalan number to the $(n,k)$-th Catalan numbers and find a combinatorial description that the $(n,k)$-th Catalan numbers is equal to the number of partitions of $n(k-1)+2$ polygon by $(k+1)$-gon where all vertices of all $(k+1)$-gons lie on the vertices of $n(k-1)+2$ polygon.
arxiv
ABSTRACT Background Globally, most people with head and neck cancers (HNCs) are diagnosed with advanced‐stage disease. HNC diagnostic stage has multifactorial explanations, with the role of health system factors not yet fully investigated. Methods HNC centres (n = 18) from the HEADSpAcE Consortium were surveyed via a bespoke health system questionnaire
Grant Creaney+201 more
wiley +1 more source
Random graphs induced by Catalan pairs [PDF]
We consider Catalan-pair graphs, a family of graphs that can be viewed as representing certain interactions between pairs of objects which are enumerated by the Catalan numbers. In this paper we study random Catalan-pair graphs and deduce various properties of these random graphs.
arxiv
Compliance with indoor and outdoor smoke-free ban in Catalan hospitals: what do patients think?
Background In Catalan hospitals, compliance with smoke-free regulation has been evaluated by direct (air markers of tobacco consumption) and indirect methods (surveys to healthcare workers); however, patients have never been asked about their insight on ...
Laura Antón+5 more
doaj +1 more source
Phantom limb pain (PLP) is a debilitating condition common after amputation that can considerably hinder patients' quality of life. Several treatments have reported promising results in alleviating PLP. However, clinical evaluations are usually performed
Max Ortiz-Catalan, Max Ortiz-Catalan
doaj +1 more source