Results 101 to 110 of about 26,285 (210)
Biotechnology Progress, EarlyView.Abstract Red blood cells (RBCs) play a critical role in oxygen and carbon dioxide transport, which is facilitated by RBC‐encapsulated hemoglobin (Hb) and carbonic anhydrase (CA). In addition, RBCs are constantly exposed to oxidative stress due to the intracellular reactive oxygen species (ROS) generated during Hb auto‐oxidation.
Mohd Asim Khan +4 more
wiley +1 more source
A Facile Protocol for C(sp2)–C(sp3) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands
ChemMedChem, EarlyView.A robust C(sp2)–C(sp3) decarboxylative coupling strategy enables access to new CRBN ligands and degraders with improved physicochemical properties. This synthetic approach is expanding the chemical space beyond C(sp2)–N linkages, fine‐tuning proteolysis‐targeting chimera activities and unlocking previously inaccessible degrader chemotypes.
Anita Maksutova +15 more
wiley +1 more source
Advantages of Exome Sequencing Over Panel Testing for Individuals With a Seizure Indication
Annals of the Child Neurology Society, EarlyView.ABSTRACT Objective Our aim was to investigate the advantages of exome sequencing versus panel testing for patients with unexplained seizures. Methods We reviewed the diagnostic outcomes of exome sequencing by a commercial genetics laboratory for more than 16 000 individuals with a clinical history of seizures or suspected seizures.
Michelle M. Morrow +8 more
wiley +1 more source
Digital Rights Activism in Multilevel Governance
European Policy Analysis, EarlyView.ABSTRACT Multilevel governance (MLG) without a clear hierarchical structure can create power imbalances among various actors, particularly in settings with overlapping jurisdictions and policy areas. This dynamic is especially pronounced in Internet governance, which faces a complex interplay of domestic laws, state interdependence, and heightened ...
Alison Harcourt
wiley +1 more source
Energy Science &Engineering, EarlyView.This review systematically explores the molecular behavior of diverse surfactants (anionic, cationic, nonionic, amphoteric) at the oil–water interface through molecular dynamics simulations. It highlights their roles in reducing interfacial tension, altering interfacial structure, and enhancing oil recovery efficiency.
Zhaowei Hou +10 more
wiley +1 more source
Flavour and Fragrance Journal, EarlyView.We unveil that CLC orchestrates the dual role of eosinophil recruitment via CCL26 and tissue remodelling via POSTN in allergic rhinitis, identifying it as a potential therapeutic target. ABSTRACT Allergic rhinitis (AR) is a chronic airway inflammation driven by a type 2 immune response, yet the molecular mechanisms underlying its persistence and tissue
Fanyu Yuan +9 more
wiley +1 more source
Assessing the adoption of the FAIR principles in Italian environmental research infrastructures. [PDF]
Patterns (N Y)Nestola E +7 more
europepmc +1 more source
Interdisciplinary Materials, EarlyView.Since solid‐state sodium batteries (SSSBs) are a promising solution for advancing sodium‐based energy storage, it is necessary to systematically summarize the development process of SSSBs. It focuses on the role of interface engineering in addressing challenges such as materials design, interfacial strategies, and multiscale characterization.
Yonghuan Fu, Guosheng Shao, Yong Lei
wiley +1 more source