Results 131 to 140 of about 2,755,565 (302)

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Alexander Dalrymple (1737-1808), hydrographer to the East India Company and the Admiralty, as publisher: a catalogue of books and charts

, 2012
This is a study of the publications and publishing practices of Alexander Dalrymple (1737-1808). Dalrymple was cumulatively a private publisher of nautical charts and plans (from 1767), the ''examiner of ships' journals'' and chart publisher for the ...
Cook, Andrew Stanley
core  

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction

Advanced Science, EarlyView.
During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao, Shenghui Huo, Yue Xing, Shuxin Zhang, Guilin Li, Yihui Liu, Chongyang Jin, Fuguang Li, Xiaoyang Ge   +8 more
wiley   +1 more source

Bodleian Library quarto catalogues I: Greek manuscripts: Catalogue of Greek manuscripts in Bodleian Library's collections. Reprinted with corrections from the edition of 1853.

, 1969
Coxe's Catalogue of the Greek manuscripts in the Bodleian Library was issued in a small number of copies, and deserves wider circulation. In making this reprint we have added the corrections which have been accumulated. The task of collating and editing
Coxe, Henry Octavius
core  

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

Advanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid, Chiara Sgattoni, Andrea Volpato, Lea Rems, Luciano A. Masullo, Eduard M. Unterauer, Rafal Kowalewski, Lucie Delemotte, Erdinc Sezgin, Ralf Jungmann, Ilaria Testa   +13 more
wiley   +1 more source

Catalogue.

, 1905
"Catalogue of the library of the Pharmaceutical Society of Great Britain. North British branch, Edinburgh. 10th ed." (p.
Pharmaceutical Society of Great Britain. Library., Pharmaceutical Society of Great Britain. North British Branch, Edinburgh. Library. Catalogue., Knapman, John William.   +2 more
core  

TAXONOMIC UPDATE OF THE SPECIES OF COPITARSIA HAMPSON 1906, (LEPIDOPTERA: NOCTUIDAE: CUCULLIINAE) ACTUALIZACIÓN TAXONOMICA DE LAS ESPECIES DE COPITARSIA HAMPSON 1906, (LEPIDOPTERA: NOCTUIDAE: CUCULLIINAE)

Gayana, 2003
The present work is a catalogue of the species of Copitarsia Hampson, including twenty-one species from North to South America. Two species group are separated taxonomically. They are the species group turbata and the species group incommoda.
Andrés O. Angulo, Tania S. Olivares
doaj  

Painting the diversity of a world's favorite fruit: A next generation catalog of cultivated bananas

Plants, People, Planet
Societal Impact Statement Bananas are nutritious fruits of major importance worldwide. Characterizing their diversity is essential to ensure their conservation and use.
Julie Sardos, Alberto Cenci, Guillaume Martin, Catherine Breton, Valentin Guignon, Ines Van den Houwe, Yaleidis Mendez, Gabriel L. Sachter‐Smith, Rachel Chase, Max Ruas, Ronan Rivallan, Janet Paofa, William Wigmore, David Tilafono Hunter, Angélique D'Hont, Nabila Yahiaoui, Christophe Jenny, Xavier Perrier, Nicolas Roux, Mathieu Rouard   +19 more
doaj   +1 more source