Results 171 to 180 of about 1,137,990 (347)

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

gcMeta 2025: a global repository of metagenome-assembled genomes enabling cross-ecosystem microbial discovery and function research. [PDF]

Nucleic Acids Res
Sun Y, Chen Q, Fan G, Sun Q, Zhou Q, Zhang J, Nie J, Ma J, Wu L.   +8 more
europepmc   +1 more source

D3.5 Report on citation enabled SSH catalogues and SSH citation exploitation

, 2021
Nicolas Larrousse, Edward J. Gray, Daan Broeder, Cesare Concordia, Jan Brase, Athina Papadopoulou   +5 more
openalex   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Suppression of CSF2RA macrophage polarisation impacts pathological cardiac remodelling in mice. [PDF]

Sci Rep
Kremastiotis G, Li Y, Bond A, Shanahan D, Gregoli KD, Poole AW, George SJ, Johnson JL.   +7 more
europepmc   +1 more source

Catalogue of older Chinese books : supplement

, 1993
Donald B. Wagner
openalex   +1 more source

Tantallon Castle, East Lothian: a catalogue of the finds

, 1992
David H. Caldwell, Marion O'Neil
openalex   +2 more sources

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Defining Wound Care Learning Objectives for Medical Students: A Multidisciplinary Comparison of Expert and Practitioner Perspectives. [PDF]

Int Wound J
Erfurt-Berge C, Mahler L, Dissemond J, Krochmann A, Conrad PV.   +4 more
europepmc   +1 more source

Retrospective /Backlog Cataloguing: The Experience at the University of Cape Coast Library, Cape Coast

, 2007
A-K Ibrahim, C Kofi
openalex   +1 more source