Results 241 to 250 of about 1,137,990 (347)

Development of interventions catalogue to reduce mechanical restraint in forensic mental health services

, 2022
Ellen Boldrup Tingleff, Frederik Alkier Gildberg   +1 more
openalex   +1 more source

Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang, Yuan Fang, Lingli Jin, Dongyang Liu, Yicheng Liu, Ruijia Zheng, Liyun Yong, Xin Wu, Longliang Qiao, Meiyan Wang, Fengfeng Cai   +10 more
wiley   +1 more source

Novel Strategy for Acquiring Metabolically-Tagged Nascent Extracellular Vesicles: Implications for Identifying Surface Protein Markers of Extracellular Vesicles From Neuroblastoma Cells Cultured With Native Serum. [PDF]

J Extracell Vesicles
Markus HP, de Jong E, Makridakis M, Frantzi M, Koçer A.   +4 more
europepmc   +1 more source

Cancer‐Like Fragmentomic Characteristics of Somatic Variants in Cell‐Free DNA

Advanced Science, EarlyView.
We report that in non‐cancerous subjects, cell‐free (cfDNA) molecules harboring somatic variants exhibit cancer‐like fragmentomic characteristics associated with clonal hematopoiesis. Importantly, these somatic variant‐associated fragmentomic aberrations are more pronounced in cancer patients. Leveraging such somatic variant‐associated signals in cfDNA,
Zhenyu Zhang, Yunyun An, Mengqi Yang, Yuqi Pan, Xiaoyi Liu, Fanglei Gong, Huizhen Lin, Bianbian Tang, Yunxia Bai, Xin Zhao, Yu Zhao, Changzheng Du, Kun Sun   +12 more
wiley   +1 more source

Tracking the evolution of an extensively drug-resistant cross-border <i>Mycobacterium tuberculosis</i> cluster, Europe, January 2016 up to August 2025: implications for European surveillance. [PDF]

Euro Surveill
Saluzzo F, Sepulcri C, Zinola A, Di Marco F, Ragazzoni L, Rossi M, Codecasa L, Cirillo DM.   +7 more
europepmc   +1 more source

A Catalogue of the Uncultivated Ferns and Fern Allies (Pteridophyta) and the Flowering Plants (Spermatophyta) of Vigo County, Indiana

, 1895
W.S. Blatchley
openalex   +1 more source

Catalogue of the Batrachia Gradientia s. Caudata and Batrachia Apoda in the collection of the British Museum

, 1882
George Albert Boulenger
openalex   +2 more sources

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

Advanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang, Gaoge Sun, Xiangzheng Liu, Shuai Zuo, Pengyuan Wang, Boxiao Zhan, Zhi John Lu, Hang Yin, Ying Zhang   +8 more
wiley   +1 more source

Illustrated Catalogue and Phylogenetic Relationships of 330 Species of Arctiinae Moth Species from the Chocó Rainforest in NW Ecuador: Most Species are Undescribed. [PDF]

Neotrop Entomol
Brehm G, Böttger D, Diniz UM, Donoso DA, Kortmann M, Müller J, Rabl D, Keller A, Laguerre M.   +8 more
europepmc   +1 more source

CD20+FCRL4+ B Cells Activate CD8+ T Cells via MHC‐I Restriction in Nasopharyngeal Carcinoma Anti‐Tumor Immunity

Advanced Science, EarlyView.
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang, Xiaotian Yuan, Kelei Gao, Bo You, Yaxuan Wang, Lai Meng, Zirong Chen, Shaobing Xie, Yunqing Liu, Zijian Dong, Shumin Xie, Ruohao Fan, Fengjun Wang, Junyi Zhang, Zhihai Xie, Yongzhen Mo, Hua Zhang, Weihong Jiang   +17 more
wiley   +1 more source