Results 31 to 40 of about 1,137,990 (347)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Multi-frequency VLBA observations of compact sources from the Peacock & Wall catalogue

, 2005
VLBA observations are presented for 6 compact radio sources selected from the Peacock & Wall catalogue. From the new morphological and spectral information 2 objects that in the Peacock and Wall catalogue are flat spectrum (alpha < 0.5) sources, appear ...
A. Rossetti, Akujor, Baum, Becker, Bogers, Bondi, C. Fanti, Carvalho, Comastri, Cotton, D. Dallacasa, Dallacasa, Dallacasa, F. Mantovani, Fanti, Fanti, Fanti, Fanti, Fanti, Fey, Fey, Fomalont, Fugmann, Giroletti, Herbig, Hummel, Hummel, Impey, Johnston, Junor, Kellermann, Kühr, Laing, Lister, Lüdke, Marcaide, Murgia, Murgia, Nan, O'Dea, O'Dea, Owsianik, Patnaik, Peacock, Peacock, Pearson, Perlman, Phillips, Piner, Polatidis, Polatidis, Pyatunina, R. Fanti, Readhead, Readhead, Sanghera, Shaffer, Snellen, Snellen, Spencer, Stanghellini, Stanghellini, Stanghellini, Stickel, Taylor, Taylor, Taylor, Tschager, von Montigny, Wiik, Wilkinson, Wilkinson, Xu   +72 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

A catalogue of butterflies (Lepidoptera, Rhopalocera) of Azerbaijan

Acta Biologica Sibirica, 2019
An annotated list of butterflies from Azerbaijan, containing 280 species, is presented. The classification and nomenclature in this work are accepted according to the key of Korb & Bolshakov (2016).
N.Y. Snegovaya, V.A. Petrov
doaj   +1 more source

A catalogue of aphid parasitoids (Hymenoptera: Braconidae: Aphidiinae) from India [PDF]

, 2011
A catalogue of aphidiine parasitoids (Hymenoptera: Braconidae: Aphidiinae) associated with various aphids species occurring in India was compiled. The present catalogue with 125 species under 22 genera has been further reinforced with not only all the ...
Akhtar, Mir Samim, Dey, Debjani, Usmani, Mohammed Kamil   +2 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Die Deutsche Zentralbibliothek für Medizin hat ihr Suchportal für Medizin und Gesundheitswesen um einen entscheidenden Schritt weiterentwickelt: Integration der Bibliothekskontofunktion in MEDPILOT [The German National Library of Medicine has extended the functions of the search portal for Medicine and Health by adding an important feature: the integration of the user accounts in MEDPILOT]

GMS Medizin – Bibliothek – Information, 2012
[english] In order to provide users fast access to the order- and account functions of the “Medicine. Health.” catalogue, the German National Library of Medicine has completely integrated these functions into the search portal MEDPILOT.
Hinnenthal, Kendra, Pössel, Jana, Schuh, Dieter   +2 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

A catalogue of software tools for digital scholarly editing

Umanistica Digitale
In the field of digital philology a large number of software tools has been developed through the years and keeps being developed in order to assist (or substitute) editors in the making of a digital scholarly edition (DSE).
Chiara Martignano
doaj   +1 more source