Results 31 to 40 of about 82,968 (253)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
A catalogue of butterflies (Lepidoptera, Rhopalocera) of Azerbaijan
Acta Biologica Sibirica, 2019 An annotated list of butterflies from Azerbaijan, containing 280 species, is presented. The classification and nomenclature in this work are accepted according to the key of Korb & Bolshakov (2016).
N.Y. Snegovaya, V.A. Petrov
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
GMS Medizin – Bibliothek – Information, 2012 [english] In order to provide users fast access to the order- and account functions of the “Medicine. Health.” catalogue, the German National Library of Medicine has completely integrated these functions into the search portal MEDPILOT.
Hinnenthal, Kendra +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
A catalogue of software tools for digital scholarly editing
Umanistica DigitaleIn the field of digital philology a large number of software tools has been developed through the years and keeps being developed in order to assist (or substitute) editors in the making of a digital scholarly edition (DSE).
Chiara Martignano
doaj +1 more source
Journal of Asia-Pacific Biodiversity, 2017 This paper provides an annotated catalogue of the plant bugs, subfamily Orthotylinae (Heteroptera: Miridae) from the Korean Peninsula. In this study, a total of 41 species are enumerated, including four new records from the Korean Peninsula ...
Sunghoon Jung +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source