Results 41 to 50 of about 59,414 (283)

Angebote auf entfernten Märkten

open access: yesÖsterreichische Zeitschrift für Geschichtswissenschaften, 2022
In the decades after 1680, barter trade led to the creation of major publishing companies in commercial hubs such as Leipzig, Nuremberg or Augsburg. Due to the increasing competition in those cities, many booksellers invested in long-distance trading ...
Mona Garloff
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Historical earthquakes in Mexico. Past efforts andnew multidisciplinary achievements

open access: yesAnnals of Geophysics, 2004
The 1985 Mexican earthquakes demonstrated that knowledge concerning their history was still scarce and precarious.In fact those earthquakes acted as triggers, because it was then when a new field of research began to develop: disaster historical research.
V. García Acosta
doaj   +1 more source

Connecting people, Trade and Orders of Knowledge: Mediality and Intermediality of Early Modern Auction Catalogues

open access: yesCromohs: Cyber Review of Modern Historiography, 2021
Auction catalogues are considered a key source in different fields of historical research and are exploited both by traditional scholarship as well as more recent, digital, big data approaches regarding the information supplied on the offered objects ...
Elizabeth Harding
doaj   +1 more source

An Index-Catalogue. [PDF]

open access: yesNature, 1888
THE regularity with which the large annual volumes of this great work reach us is most reassuring, and now its completion in some six more years may be looked upon as practically certain, considering the vast resources of the United States, and the energy which its editors have shown.
openaire   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

A deep learning approach to photo–identification demonstrates high performance on two dozen cetacean species

open access: yesMethods in Ecology and Evolution, 2023
Researchers can investigate many aspects of animal ecology through noninvasive photo–identification. Photo–identification is becoming more efficient as matching individuals between photos is increasingly automated.
Philip T. Patton   +56 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Publishers’ catalogues gathered by Antoine-Augustin Renouard and the re-discovery of an Aldine Sammelband

open access: yesTECA
The article focuses on the collection of sixteenth-century publishers’ catalogues gathered by Antoine-Augustin Renouard (1765-1853) and, more specifically, on its dispersion, with the aim of reconstructing the history and current location of his copies ...
Ester Camilla Peric
doaj   +1 more source

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