Results 221 to 230 of about 188,905 (295)

Assessing Patient Safety Culture in Hospital at Home Services Across Spain Through a National Survey. [PDF]

Nurs Health Sci
Granel N, Sanchez Martos EA, Subirana-Casacuberta M, Watson CE, Gomez-Ibáñez R, Risco E.   +5 more
europepmc   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

Brain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga, Eva Fernández‐Muñoz, Jorge M. Charco, Enric Vidal, Diego Herrero‐Martínez, Josu Galarza‐Ahumada, Cristina Sampedro‐Torres‐Quevedo, Samanta Giler, Mariví Geijo, Gloria González‐Aseguinolaza, Hasier Eraña, Joaquín Castilla   +11 more
wiley   +1 more source

Use of anti-nucleocapsid antibody detection as a marker of SARS-CoV-2 infection in healthcare professionals: a longitudinal seroprevalence study at a university hospital in Catalonia, Spain. [PDF]

BMC Infect Dis
Micó M, Trapé J, González-García L, Trujillo-Isern G, González-Fernández C, López-Madueño J, Bérgamo S, Pérez-Vidal R, Flor A, Martínez-Montero R, Rives J, Arnau A, Fàbrega A, Althaia Serology Group.   +13 more
europepmc   +1 more source

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

Brain Pathology, EarlyView.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña, Enric Vidal, Natalia Fernández‐Borges, Jorge M. Charco, Carlos M. Díaz‐Domínguez, Cristina Sampedro‐Torres‐Quevedo, Josu Galarza‐Ahumada, Eva Fernández‐Muñoz, Maitena San‐Juan‐Ansoleaga, Miguel Ángel Pérez‐Castro, Nuno Gonçalves‐Anjo, Patricia Piñeiro, Samanta Giler, Nora González‐Martín, Nuria L. Lorenzo, Africa Manero‐Azua, Guiomar Perez de Nanclares, Mariví Geijo, Manuel A. Sánchez‐Martín, Jesús R. Requena, Joaquín Castilla   +20 more
wiley   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

Brain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira, Yaiza López‐Sampere, Pol Mengod‐Soler, Mario Peña‐Fonteboa, Carla Marco, Alejandro Caravaca‐Puchades, Raúl Domínguez, Juan Francisco Vázquez‐Costa, Enrique Santamaría, Joaquín Fernández‐Irigoyen, María J. Colomina, Isabel León Moreno, Antonio Martínez Yélamos, Sergio Martínez Yélamos, Gabriel Santpere, Elia Obis, Manuel Portero‐Otín, Gerard Piñol‐Ripoll, Mónica Povedano, Pol Andrés‐Benito   +19 more
wiley   +1 more source

Primary Care Records and Population Prevalence of Chronic Insomnia: Do They Match? [PDF]

Healthcare (Basel)
Pujol Salud J, García-Serrano C, de Entrambasaguas M, Malla Montagut M, Martínez Redondo J.   +4 more
europepmc   +1 more source

Cumulative effect of multiple health and social factors on adolescent mental well‐being: a cross‐sectional study in Catalonia

Child and Adolescent Mental Health, EarlyView.
Background While numerous studies have explored factors contributing to poor mental health, few have examined the combined influence of multiple health and social factors and their cumulative effect. This study specifically aimed to analyze the cumulative effect of multiple health and social factors associated with poor mental well‐being in school‐aged
Marina Robles‐Muñoz, Marina Bosque‐Prous, Cinta Folch, Helena González‐Casals, Gemma Drou‐Roget, Cristina Torrado‐Cortés, Carles Muntaner, Albert Espelt   +7 more
wiley   +1 more source

Expectations and Concerns of Adoptive Families of Children With Fetal Alcohol Spectrum Disorder

Child &Family Social Work, EarlyView.
ABSTRACT Fetal alcohol spectrum disorder (FASD) is considered a condition that persists throughout life in people who have been exposed to alcohol during the gestation period. During the different stages of their lives, individuals with FASD face different challenges and adversities that—without the right resources and strategies—can contribute to ...
Dídac Gómez‐Santabrígida, Carme Montserrat, Marta Garcia‐Molsosa, Gala Lima‐López   +3 more
wiley   +1 more source

Exploring the association of antibiotic consumption on resistance: evidence from Catalonia (Spain) using a threshold regression approach. [PDF]

BMJ Public Health
Mora T, Roche D, Cabezas Peña C, López-Valcárcel BG.   +3 more
europepmc   +1 more source

Child Protection System and Education: An Umbrella Review of Factors Supporting the Educational Progress of Children in the Foster Care System

Child &Family Social Work, EarlyView.
ABSTRACT International literature has consistently demonstrated that children in the foster care system (FCS) exhibit poorer academic outcomes: lower academic achievement, higher rates of school absenteeism and truancy, lower high school graduation rates and reduced postsecondary educational attainment.
Antonieta Candia‐Fonseca, Laura Arnau‐Sabatés, Josefina Sala‐Roca   +2 more
wiley   +1 more source